Administrative and Service Core

弗吉尼亚大学核心研究所的首席研究员Lee博士将与 Drs.埃默里大学行政和服务核心A的联合主任Chung和彼得罗斯， 从方案项目中产生的数据，将储存在位于 埃默里大学泌尿外科和卫生系统。数据分析将在两个 埃默里大学和弗吉尼亚大学基于先进的统计计算环境， 包括S-PLUS，一种面向对象的统计软件（Insightful，Inc.;华盛顿州西雅图）和其他节目 软件埃默里大学公共卫生学院和健康评估科学系， 弗吉尼亚大学有自己NT服务器，有72 GB的冗余阵列磁盘空间和1 GB的RAM。向各部门提供了一个具有1千兆字节RAM和S+及SAS的UltraSpard 用于CPU密集型计算的成员。分析结果和报告将提供给项目 并存储在埃默里的中央数据库中。李博士将提供生物统计学和生物信息学 支持，包括实验设计和数据分析，如每个研究项目的目的所述 以及微阵列和组织阵列来寻找在细胞培养/动物模型中差异表达的基因， 在临床标本中。李博士是一位长期合作者，经验丰富的生物统计学家， 微阵列/基因芯片设施在弗吉尼亚大学，和罗伯特博士莱尔斯，一位经验丰富的生物统计学家 来自埃默里大学公共卫生学院的专家将就需要他们投入的项目进行咨询和合作。

Dr. Lee, Principal Investigator of the Core A subcontract at University of Virginia, will communicate with Drs. Chung and Petros, Co-Directors of the Administrative and Services Core A at Emory University, to archive data generated from the program projects, which will be stored at the central database system located in the Urology Department at Emory University and Health System. Analyses of the data will be conducted at both Emory University and the University of Virginia based on an advanced statistical computing environment, including S-PLUS, an object-oriented statistical software (Insightful, Inc.; Seattle, WA) and other programming software. The Emory University School of Public Health and the Department of Health Evaluation Sciences at the University of Virginia have their own NT server with 72 gigabytes of Redundant Array Disk space and 1 gigabyte of RAM. An UltraSpard with 1 gigabyte of RAM and S+ and SAS is available to department members for CPU-intensive computations. The analysis results and reports will be provided to Project Directors and stored at the central database at Emory. Dr. Lee will provide biostatistical and bioinformatics support, including experimental designs and data analysis, as described in the Aims of each research project and microarray and tissue array to seek for genes differentially expressed in the cell culture/animal models and in clinical specimens. Dr. Lee, a long-term collaborator and an experienced biostatistician and the director of microarray/GeneChip facility at the University of Virginia, and Dr. Robert Lyles, an experienced biostatistician from Emory University School of Public Health will consult and collaborate on projects that need their input.