Environment and Perceived Control: Improving Sleep in Hospitalized Older Patients

描述（由申请人提供）：本申请的目的是支持Vineet Arora， MD， MA，芝加哥大学接受奖学金培训的学术医院医生的以患者为导向的研究计划和职业发展。阿罗拉博士的总体目标是成为一名独立的研究人员，专注于描述和改善老年住院患者的睡眠时间和睡眠质量。阿罗拉博士将在Eve Van Cauter博士的指导下发展她的研究技能，Eve Van Cauter博士是正常和病理状态下睡眠和昼夜节律的知名权威，专注于老年人的睡眠。David Meltzer，医学博士，一位在医院医学和卫生经济学研究方面有成就的研究者，专注于老龄化，将担任共同导师。阿罗拉博士还将受益于一个顾问团队在老年人临床护理和研究方面的集体专业知识。格雷格·萨克斯，埃里克·科尔曼和丹尼尔·布劳纳。她还将从一组合作者那里获得必要的培训和研究技能，这些合作者包括：(1)Babak Mokhlesi医学博士，睡眠医学奖学金主任，他将使阿罗拉博士获得睡眠医学的正式培训；(2) Kristen Knutson博士，研究人员和人类学家，专门研究使用活动记录仪和睡眠量表来量化睡眠持续时间和质量；(3)统计分析专家Anirban Basu博士。在拟议的奖励期间，阿罗拉博士将通过芝加哥大学的结构化课程和课程获得睡眠医学，健康服务研究和老年病学方面的正式培训。本研究计划的总体目标是阐明环境、医疗保健和患者因素，以及患者的感知控制水平，如何影响住院老年患者的睡眠持续时间和睡眠质量。此外，还将描述住院老年患者的住院睡眠（持续时间和质量）与结果（身体活动和其他健康结果）之间的关系。通过这一时期的职业发展和研究，阿罗拉博士将能够更好地了解住院睡眠的决定因素和影响，这可以使基于证据的干预措施的设计成为可能，旨在改善住院老年人的住院睡眠和相关结果。

DESCRIPTION (provided by applicant): The purpose of this application is to support the patient-oriented research program and career development of Vineet Arora, MD, MA, a fellowship-trained academic hospitalist at the University of Chicago. Dr. Arora's overall goal is to develop into an independent investigator with a focus on characterizing and improving sleep duration and sleep quality for older hospitalized patients. Dr. Arora will develop her research skills under the mentorship of Eve Van Cauter, PhD, a well-known authority on sleep and circadian rhythms in normal and pathologic states, with a focus on sleep in older persons. David Meltzer, MD, PhD, an accomplished investigator in research in hospital medicine and health economics with a focus on aging, will serve as a co- mentor. Dr. Arora will also benefit from the collective expertise in clinical care and research of older persons from a team of advisors, including Drs. Greg Sachs, Eric Coleman, and Daniel Brauner. She will also obtain necessary training and research skills from a team of collaborators including: (1) Babak Mokhlesi, MD, Director of the Sleep Medicine Fellowship, who will enable Dr. Arora to obtain formal training in sleep medicine; (2) Kristen Knutson, PhD, a research faculty and anthropologist who specializes in the use of actigraphy and sleep scales to quantify sleep duration and quality; and (3) Anirban Basu, PhD, an expert in statistical analysis. During the proposed award, Dr. Arora will obtain formal training in sleep medicine, health services research, and geriatrics through structured curricula and coursework at the University of Chicago. The overall goal of this research proposal is to elucidate how environmental, healthcare, and patient factors, in addition to a patients' level of perceived control, impact sleep duration and sleep quality in hospitalized older patients. In addition, the relationship between inpatient sleep (duration and quality) and outcomes (physical activity and other health outcomes) for hospitalized older patients will be characterized. Through this period of career development and research, Dr. Arora will be able to better understand the determinants and effects of in- hospital sleep which can enable the design of evidence-based interventions that aim to improve in-hospital sleep and associated outcomes for hospitalized older adults. PUBLIC HEALTH RELEVANCE: The overall goal of this research proposal is to elucidate how environmental, healthcare, and patient factors, in addition to a patients' level of perceived control, impact sleep duration and sleep quality in hospitalized older patients. In addition, the relationship between inpatient sleep (duration and quality) and outcomes (physical activity and other health outcomes) for hospitalized older patients will be characterized. Through this period of career development and research, Dr. Arora will be able to better understand the determinants and effects of in-hospital sleep which can enable the design of evidence-based interventions that aim to improve in-hospital sleep and associated outcomes for hospitalized older adults.