C1/A: Administrative Core

行政核心通过强有力的领导，在指导孢子调查方面发挥核心作用 和有效的项目管理。李博士、卡塔罗纳博士和斯塔德勒博士在这方面拥有丰富的专业知识。 针对上一次提交的评审员的意见，我们详细描述了 对所有项目进行评估。行政核心是一个主动的指挥结构，它使必要的 决定集中和优化孢子研究活动，使其与高度优先事项保持一致 独立确定的领域/目标，以及与NCI领导层、内部和 外部咨询委员会。核心促进了不同项目和核心之间的互动， 为孢子调查员提供适当的行政协助，并管理所有孢子 财务方面。核心负责发展研究和职业生涯的管理 发展计划。核心的领导强调在科学生产力方面的最高质量 转化性/介入性前列腺癌研究和掌握孢子项目的进展 通过协调孢子月度会议和内部咨询委员会和 外部咨询委员会。具体目标是： 整合孢子调查员，鼓励孢子内和孢子间的相互作用 ？为孢子计划提供方向和指导，以促进科学进步 ？提供接触外部前列腺癌研究人员的外展机会 ？指导发展研究和职业发展方案，使新的和 转译前列腺癌研究吸引了老牌研究人员 ？为所有孢子项目和核心提供财务和行政监督 ·领导每月的孢子会议，交流科学信息 ·领导内部和外部咨询委员会的会议 ？向NCI提交必要的进度报告和其他文件 ？进行必要的改革，以保持高质量的研究水平，并确保 孢子的翻译目标正在实现，包括分配可自由支配的资金。 ？安排与其他主要机构计划的合作，例如加州大学的SPECS计划 北卡罗来纳大学癌症纳米技术卓越中心和DeCode Genetics in 冰岛。

The Administrative Core maintains a central role in guiding SPORE investigators through strong leadership and effective program management. Drs. Lee, Catalona and Stadler have significant expertise in this regard. In response to reviewers' comments in the last submission, we have described in detail the criteria for evaluation of all projects. The Administrative Core is an active command structure that makes the necessary decisions to focus and optimize SPORE research activities in order that they align with high priority areas/goals identified independently, as well as in cooperation with the NCI leadership, the Internal, and the External Advisory Committees. The Core facilitates interactions among the different projects and cores, provides appropriate administrative assistance to investigators in the SPORE and manages all SPORE finances. The Core is responsible for the administration of the Developmental Research and the Career Development Programs. The Core's leadership emphasizes the highest quality in scientific productivity in translational/interventional prostate cancer research and keeps abreast of progress of SPORE projects through coordinating SPORE monthly meetings and meetings of the Internal Advisory Committee and the External Advisory Committee. The specific aims are: ¿ To integrate SPORE investigators and encourage intra-SPORE and inter-SPORE interactions ¿ To provide direction and guidance to the SPORE program to promote scientific progress ¿ To provide outreach opportunities to engage outside prostate cancer researchers ¿ To direct the Developmental Research and Career Development Programs such that both new and established investigators are attracted to translational prostate cancer research ¿ To provide financial and administrative oversight for all SPORE projects and Cores ¿ To lead monthly SPORE meetings to exchange scientific information ¿ To lead the meetings of the Internal and External Advisory Committees ¿ To submit necessary progress reports and other documents to the NCI ¿ To institute changes necessary to maintain a high level of quality research and ensure that the translational goals of the SPORE are being met, including allocation of discretionary funds. ¿ To arrange collaborations with other major institutional programs, such as the SPECS program at UC Irvine, the NU Center of Cancer Nanotechnology Excellence {CCNE}, and deCODE Genetics in Iceland.