Wallace Tumor Institute Rodent Housing and Procedure Equipment

描述(申请人提供)：重要的生物医学研究和科学数据的完整性依赖于出色的动物护理。阿拉巴马大学伯明翰分校(UAB)动物护理和使用计划致力于实现长期目标，即根据公认的标准，以合理的成本提供和维护始终如一的高质量、健康的动物，同时为工作人员提供安全和健康的工作场所，对环境的影响最小。所需设备、20个排气通风笼养系统(EVCS)、7个通风动物转运站(VAT)和3个生物安全柜(BSC)将有助于实现这些长期目标和本提案的具体目标。本申请中建议的设备将使位于华莱士肿瘤研究所的UAB癌症中心成员受益，他们使用MICE(18名调查人员，7个部门，目前在其他建筑中饲养的约1700笼啮齿动物)。它还将使使用小动物成像核心设施的21名癌症中心成员受益。所需设备将有助于完成93个在建项目(1850万美元)和63个待决项目(7540万美元)。所要求的设备将是维持和支持国家和国际公认的跨学科研究计划发展所需的基础设施的一部分。

DESCRIPTION (provided by applicant): Vital biomedical research and integrity of scientific data depend on excellent animal care. The University of Alabama at Birmingham (UAB) Animal Care and Use Program is committed to the long-term goals of providing and maintaining consistently high quality, healthy animals according to accepted standards at reasonable cost while providing a safe and healthy workplace for personnel with minimal impact on the environment. The equipment requested, 20 exhaust ventilated caging systems (EVCS), 7 ventilated animal transfer stations (VATS) and 3 biological safety cabinets (BSCs) will assist in attaining these long term goals and the specific aims of this proposal. The equipment proposed in this application will benefit UAB Cancer Center members located in Wallace Tumor Institute who use mice (18 investigators, 7 departments, ~1700 cages of rodents currently housed in other buildings). It will also benefit 21 Cancer Center members who use the small animal imaging core facility. The requested equipment will contribute to the completion of 93 active ($18.5M) and 63 pending ($75.4M) projects. The requested equipment will be a part of the infrastructure needed to maintain and support the growth of a nationally and internationally recognized interdisciplinary research program.