OR/WA COLLABORATIVE GENETICS RESEARCH PROGRAM

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 OR/WA协作遗传学研究计划是由华盛顿和俄勒冈州国家灵长类动物研究中心共同资助的一项共同努力。该计划的目的是发展和支持两个中心的遗传研究调查，并促进两个中心之间的合作项目。该计划包括：1）改进用于遗传研究的基因分型方法，2）启动表型研究以确定潜在的动物模型并开发新的遗传研究项目，3）为研究人员启动的遗传研究提供技术培训和专业知识。 在过去的一年中，我们开发了ONPRC和WaNPRC之间的合作，以探索在两个NPRC的猕猴自发SIB的遗传基础。 已收集受试者病史和DNA样本，基因型分析正在进行中。 我们还启动了一项扩展的SNP测定，用于验证NPRC研究中恒河猴的血统。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The OR/WA Collaborative Genetics Research Program is a joint effort funded equally by the Washington and Oregon National Primate Research Centers. The purpose of this program is to develop and support genetic research investigations at both Centers and to promote collaborative projects between the two centers. The program encompasses 1) improving genotyping methods for use in genetic studies, 2) initiating phenotypic studies to identify potential animal models and to develop new genetic research projects, 3) providing technical training and expertise for investigator initiated genetic research. In the past year, we developed a collaboration between the ONPRC and the WaNPRC to explore the genetic basis of spontaneous SIB in macaques at both NPRCs. Subject history and DNA samples have been collected genotype analysis is underway. We also launched an expanded SNP assay for verifying the ancestry of rhesus macaques for the NPRC studies.