2012 Cornea, Biology & Pathobiology GRC

描述(由申请人提供)：本提案请求部分支持将于2012年3月25日至30日在加利福尼亚州文图拉举行的2012年戈登角膜生物学和病理生物学研究会议。本次会议的广泛和长期目标是促进角膜健康研究的创新，将该领域的世界领先的研究人员和受训人员以一种小型的形式聚集在一起，使跨学科的讨论和合作成为可能，从而提高我们对角膜生物学和病理生物学的理解，以及如何利用这些知识来维持角膜健康，从而提高视力。具体目标将是召集负责该领域关键领域的主要专家和受训人员，共有150人参加，在相对孤立的环境中举行为期五天的会议。该计划将分为九个环节，涉及基础研究和临床应用、角膜发育、系统生物学、干细胞、屏障功能、透明度、分泌物、蛋白质组学和代谢组学、感染和炎症、干眼、伤口愈合、建模和工程、再生和重建方面的挑战。被邀请的演讲者将包括视觉科学领域内外的专家，他们拥有与先进的角膜研究相关的专业知识。更多的演讲者时段将用于从摘要提交中挑选出的最新热点话题。下午的海报会议将允许所有参与者贡献自己的力量。将尽一切努力鼓励研究生和博士后研究员参与，使妇女人数均等，并将少数群体和残疾人包括在内。创新在于将相对较少的科学家和受训人员聚集在一起，他们对角膜有共同的兴趣。其他会议的规模要大得多，集中在整个眼睛和/或视力、临床护理或与角膜研究相关的特定主题上。这一应用的意义在于，戈登研究会议将为专注于角膜及其支持组织的科学家和学员提供一个论坛，交流想法，会见与了解角膜生物学相关的研究领域外的专家，并开展富有成效的合作，进一步推动角膜研究领域的发展，帮助将基础科学发现转化为临床实践，并改善国内和国际的视力护理。这项提议的目的是确保会议的部分资金，以支付研究生、受训人员和其他非NEI资助的主要调查人员的注册费和/或旅费。 与公众健康相关：角膜的健康状况对视力至关重要。戈登角膜生物学和病理生物学研究会议不同于该领域的其他会议，因为它是一个小型但极其全面的会议，涵盖角膜生物学研究的方方面面，包括基础科学及其对维持或恢复角膜健康的战略的转化。通过将领先的科学家和 来自世界各地的受训者将以一种能够分享结果和想法并建立新的合作关系的形式，通过这次会议将导致对角膜的更好的了解，这将加速旨在减少角膜失明的研究。

DESCRIPTION (provided by applicant): This proposal requests partial support for the 2012 Gordon Research Conference on the Biology and Pathobiology of the Cornea to be held in Ventura, California, March 25-30, 2012. The broad and long-term goal of this conference is to foster innovation in corneal health research by bring together the world's leading researchers and trainees in this field in a small format that enables cross-disciplinary discussions and collaborations so as to improve our understanding of corneal biology and pathobiology and how such knowledge could be leveraged to maintain corneal health and therefore vision. The specific aims will be to convene leading experts covering critical areas within this field and trainees, with a total of 150 participants for a five-day conference in a relatively isolated settig. The program will be structured into nine sessions addressing challenges in basic research and clinical application, corneal development, systems biology, stem cells, barrier function, transparency, secretion, proteomics and metabolomics, infection and inflammation, dry eye, wound healing, modeling and engineering, regeneration and reconstruction. Invited speakers will include experts both inside and outside the vision science field with expertise relevant to advancing corneal research. Additional speaker slots will be available for late breaking hot topics selected from abstract submissions. Afternoon poster sessions will permit all participants to contribute. Every effort will be made to encourage participation by graduate students and postdoctoral fellows, to have parity in the numbers of women, and to include minorities and persons with disabilities. Innovation lies in the concept of bringing together a relatively small group of scientist and trainees with a common interest in the cornea. Other meetings are significantly larger, focused on the whole eye and/or vision, on clinical care, or on specific topis relating to corneal research. The significance of this application is that this Gordon Research Conference will enable a forum for scientist and trainees focused on the cornea and its supportive tissues to exchange ideas, meet experts from outside the field whose research relates to understanding corneal biology, and to develop productive collaborations to further advance the field of corneal research and help translate discoveries in basic science to clinical practice and improve vision care nationally and internationally . The aim of this proposal is to secure partial funding for the conference to cover registration fees and/or travel costs for graduate students, trainees and other participants who are not NEI-funded principal investigators. PUBLIC HEALTH RELEVANCE: The heath of the cornea is critical to vision. The Gordon Research Conference on the Biology and Pathobiology of the Cornea differs from other conferences in this field in that it is a small yet intensely comprehensive meeting covering all aspects of corneal biology research, including the basic sciences and their translation to strategies for maintaining or restoring corneal health. By bringing together leading scientists and trainees from around the globe in a format that enables results and ideas to be shared, and new collaborations to be forged, this meeting will lead to a better understanding of the cornea which should accelerate research aimed at reducing the incidence of corneal blindness.