Pediatric Gastroenterology and Nutrition Training Grant

描述（由申请人提供）：该儿科胃肠病学培训基金旨在提供密集的基础或以患者为基础的研究经验，这对于临床医生和科学家在学术和调查医学领域的生产和独立职业生涯至关重要。该项目在招聘训练有素的临床医生并为他们提供研究机会、教育课程和指导方面有着良好的记录，使他们能够实现成功的学术生涯。该项目将支持辛辛那提儿童医院医学中心的7名博士后。这些研究员将在实验室或结构化临床研究项目中与指导老师一起度过两年。教师顾问由44名研究兴趣与儿科胃肠病学相关的研究人员组成。该方案的核心主题重点领域是：1)慢性肝病，2)消化器官（肝脏和肠道）衰竭和移植，3)炎症和腹泻疾病，以及4)肥胖。一个完全对齐的消化疾病研究核心中心（PSO）的存在进一步提高了学术环境和培训计划的重点。该学院在富有成效的合作和校外资助方面有着良好的记录。一组非常合格的准（副）教师顾问也已确定，以确保该计划的持续增长。该项目的行政核心包括一名项目总监和副项目总监（co-PI），他们在战略和运营上共同努力，以确保项目的强大。基础研究和临床研究方面的学员都需要讲授性课程，并辅以适当的研讨会、期刊俱乐部、负责任的研究行为课程和其他充实课程。那些学习如何进行以病人为基础的研究的人有望获得理学硕士学位。我们的学员在学术医学（75%）和进行研究（61%）方面的记录是我们成功的衡量标准。我们还履行了培训妇女（44%）和少数民族（22%）的承诺。有一群高素质的候选人申请和/或已经承诺进入我们的临床培训计划。因此，考虑到我们的机构资源和过去的成功，该计划准备扩大培训机会，以增加儿科胃肠病学新研究者的数量。

DESCRIPTION (provided by applicant): This Training Grant in Pediatric Gastroenterology is designed to provide an intensive basic or patient based research experience that is essential to prepare clinician-scientists for productive and independent careers in academic and investigative medicine. The Program has a demonstrated track record of recruiting well-trained clinicians and providing them with research opportunities, an educational curriculum and mentoring to enable them to achieve successful academic careers. The program will support 7 postdoctoral fellows at Cincinnati Children's Hospital Medical Center. These fellows will spend two years with a Faculty Advisor in the laboratory or a structured clinical research program. The Faculty Advisors consist of 44 investigators with research interests relevant to pediatric gastroenterology. The thematic focus areas central to the Program: are 1) Chronic liver disease, 2) Digestive organ (liver and intestinal) failure and transplantation, 3) Inflammatory and diarrheal diseases, and 4) Obesity. The presence of a fully aligned Digestive Disease Research Core Center (PSO) further enhances the academic environment and focus of the training program. The Faculty has a demonstrated record of productive collaboration and extramural funding. A group of well- qualified prospective (associate) Faculty Advisors has also been identified to ensure continued growth of the program. The Administrative Core of the Program includes a Program Director and Associate Program Director (co-PI) who work both together both strategically and operationally to ensure a strong program. Didactic course work is required for trainees in both basic and clinical research and this is supplemented with appropriate seminars, journal clubs, a course in the responsible conduct of research, and other enrichment offerings. Those learning how to perform patient based research are expected to complete a Master of Science Degree. The record of our Trainees in staying in academic medicine (75%), and performing research (61%) is a measure of our success. We have also fulfilled our commitment to training women (44%) and minorities (22%). There is a pool of highly qualified candidates applying to and/or already committed to entering our clinical training program. Thus, when considered with our institutional resources and past success, the Program is poised to extend the training opportunities to increase the number new investigators in Pediatric Gastroenterology. PUBLIC HEALTH RELEVANCE: There is a critical shortage of investigators in pediatric gastroenterology who can advance new knowledge to improve the outcomes for children with digestive diseases. Our training program focuses on 1) Chronic liver disease, 2) Liver and intestinal failure and transplantation, 3) Inflammatory bowel disease, eosinophilic gastrointestinal and diarrheal disorders, and 4) Obesity. We will provide mentored training to pediatricians who will become the next generation of investigators in pediatric gastroenterology.