Institutional Training Grant in Pediatric Gastroenterology

本申请书是第一次更新儿科机构培训计划(T32)。 科罗拉多大学丹佛分校的胃肠病学、肝病和营养学 科罗拉多州奥罗拉市安舒茨医学院的一家医院。该计划的总体目标是 为不同的博士后实习生群体提供卓越的监督培训体验 使他们能够发展或提高他们的研究技能和知识，为 儿科胃肠病或肝病相关研究经历。这样做的根本理由是 计划是利用新的Anschutz Medical提供的新的物理和科学协同效应 校园，一支杰出的、敬业的、经验丰富的研究人员，以及一大批潜在的申请者。 提供两种研究培训途径，以培养基础实验室科学家或临床- 翻译科学家。研究培训将集中在五个科学主题：发病机制和 小儿肝病的治疗，小儿肠病的免疫发病机制，粘膜 免疫生物学、儿童肥胖和代谢综合征及健康结局研究。T32教职员工 由25名个人组成，在R01、U01或计划项目赠款资金中拥有超过2700万美元的资金，以及 非常成功的训练记录。基础研究经验通过研究生课程、研讨会得到加强 和多学科会议。临床-翻译研究的实习生将参加大师赛 临床科学研究生项目的学位，并将利用科罗拉多州的基础设施 临床与翻译科学研究所。研究培训计划设计为2-3年 课程，一般从2“”*年的副专业奖学金开始，或在完成博士或 等价物。符合条件的候选人主要来自国家承认的儿科奖学金 胃肠病学，具有其他学科的候选人的潜力，包括新生儿学，营养学和 相关基础科学领域。为学员提供至少80%的保护时间，为期2或3年 在有指导和有组织的环境中进行培训。教育和研究体验的质量 将由实习生、导师和执行委员会通过定义的指标和 持续改进流程。在过去3年内完成T32培训的7名学员中， 5人拥有全职学术职位，并很早就开始了他们的研究生涯。续集 请设4个培训职位，并在第二年增设一个5“^职位，以便接受3年的培训。 相关性(请参阅说明)： 该T32培训计划通过培训下一代医生和博士来与儿童健康相关 科学家们将通过科学发现促进对患有GL、肝病和 营养失调。本培训项目对研究性培训的投入将为 为了让学员成为未来的领导者、教师和导师，帮助指引Gl的方向， 未来的肝病和营养学。

This application is for the first renewal of the Institutional Training Program (T32) in Pediatric Gastroenterology, Hepatology and Nutrition at the University of Colorado Denver and The Children's Hospital at the Anschutz's Medical Campus in Aurora, Colorado. The overall goal of this program is to provide a diverse group of post-doctoral trainees with an exceptional supervised training experience to allow them to develop or enhance their research skills and knowledge in preparation for a pediatric gastroenterology or hepatology related research career. The underlying rationale for this program is to take advantage of new physical and scientific synergies provided by the new Anschutz Medical Campus, an outstanding committed experienced research faculty, and a large pool of potential applicants. Two pathways of research training are offered to produce Basic Laboratory Scientists or Clinical- Translational Scientists. Research training will be focused in five scientific themes: pathogenesis and treatment of pediatric liver disease, immunopathogenesis of pediatric intestinal disease, mucosal immunobiology, pediatric obesity and metabolic syndrome and health outcomes research. The T32 faculty comprises 25 individuals with over $27 million dollars in R01, U01 or program project grant funding and a highly successful training record. Basic research experiences are augmented by graduate courses, seminars and multidisciplinary meetings. Trainees in clinical-translational research will participate in the Masters Degree in the Clinical Sciences Graduate Program and will leverage the infrastructure of the Colorado Clinical and Translational Sciences Institute. The research training program is designed to be a 2-3 year program, generally beginning in the 2""* year of subspecialty fellowship or following completion of a PhD or equivalent. Eligible candidates are primarily drawn from the nationally recognized fellowship in Pediatric Gastroenterology, with the potential for candidates in other disciplines including neonatology, nutrition and related basic science fields. Trainees are provided a minimum of 80% protected time for 2 or 3 years of training in a mentored and structured environment. The quality of the educational and research experiences will be closely monitored by the trainees, mentors and Executive Committee with defined metrics and ongoing improvement processes. Of the 7 trainees who have completed the T32 training in the past 3 years, 5 have full-time academic positions and are very early in developing their research careers. The continuation of 4 training positions is requested with the addition of a 5"^ position in year 2 to allow for 3 years of training. RELEVANCE (See instructions): This T32 Training Program is relevant to child health by training the next generation of physician and PhD scientists who through scientific discovery will advance the care of children with Gl, hepatology and nutritional disorders. The investment in research training in this Training Program will provide a foundation for the trainees to become the future leaders, teachers and mentors who will help guide the direction of Gl, hepatology and nutrition in the future.