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Computational modeling of human metabolism, body weight and composition

Computational modeling of human metabolism, body weight and composition
人体新陈代谢、体重和成分的计算模型
批准号：
8349651
负责人：
KEVIN HALL
金额：
$34.13万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8349651
关键词：
AffectAnorexia NervosaBehaviorBiological SciencesBody CompositionBody WeightBody Weight ChangesCachexiaClinicalClinical InvestigatorClinical ManagementClinical ResearchClinical SciencesCollaborationsComplexComputer SimulationDataDiseaseEatingEnergy IntakeEnergy MetabolismEngineeringGoalsHumanInterventionKnowledgeLifeMacronutrients NutritionMeasurementMetabolicMetabolic DiseasesMetabolismModelingObesityProspective StudiesPublishingRegulationResearchSystemUnited States National Institutes of HealthWasting SyndromeWeightdesignmathematical modelphysical scienceprogramsresearch studyresponsetoolvalidation studies

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中文摘要
翻译
我们继续开发人体代谢的数学模型，并使用各种已发表的数据进行了验证研究的代谢反应，过度喂养，喂养不足，和等热量的饮食常量营养素的变化。我们的模型已被部署为与NIH临床研究人员合作的临床研究工具，以帮助设计前瞻性研究以及计划和跟踪临床体重管理计划。我们的模型正被应用于各种问题，从计算人类体重变化和食物摄入量之间的关系，到使用频繁的体重测量来计算自由生活能量摄入量的变化。
英文摘要
We continue to develop mathematical models of human metabolism and have conducted several validation studies using a variety of published data on the metabolic responses to overfeeding, underfeeding, and isocaloric changes in dietary macronutrients. Our models have been deployed as a clinical research tool in collaboration with NIH clinical investigators to help design prospective studies as well as plan and track clinical weight management programs. Our models are being applied to a variety of problems, from calculating the relationship between human weight change and food intake to calculating changes of free-living energy intake using frequent body weight measurements.
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会议论文
Interactions of diet, exercise, metabolism, and weight change in humans
Regulation of rodent energy metabolism, body weight and composition
Computational modeling of human metabolism, body weight and composition
Regulation of rodent energy metabolism, body weight and composition
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