Technology Transfer

技术转让办公室共处理了333份材料转让协议和保密协议。NIDCR保持出料与进料的比例约为5:1。据我们所知，2011财年有5项新的许可被执行，其中包括nih首次向私营公司独家许可干细胞技术。2011财年的特许权使用费总额预计将超过NIDCR技术转让办公室的分配预算。提交了9份员工发明报告，包括针对Sjgrens综合征，口干症和糖尿病的发明。一个显著的成就是树脂干扰素（RTX）成功转让给一家私营公司，该公司首先涉及nih，将孤儿药指定与独家许可结合起来，签署了一份协议，在临床中心、NINDS和NIDCR之间建立了伙伴关系，NIDCR与被许可方一起为RTX NINDS CRADA提供了科学、临床和财务支持。办公室工作人员努力提醒管理层注意技术转让预算中专利费用中的重大超额义务，这产生了积极的影响：美国国立卫生研究院技术转让办公室正在制定监测义务解除的指标，并与许可证和专利管理人员沟通，以确定减少不必要的超额义务的方法。由于大量使用技术转让服务以及新实施的NIH和NIDCR材料转让政策改进了监督，工作量增加，技术转让办公室在2011财年填补了一个全职技术开发专家职位。

NIDCRs technology transfer office processed 333 material transfer agreements and confidentiality agreements. NIDCR maintains an approximate 5:1 ratio of outgoing materials as compared to incoming materials. There were 5 new licenses executed in FY2011, includingto our knowledge--the NIHs first exclusive license of a stem cell technology to a private company. Total royalties for FY2011 are expected to exceed the allocated budget for the NIDCR technology transfer office. Nine Employee Invention Reports were filed, including inventions directed towards Sjgrens Syndrome, xerostomia, and diabetes. A notable achievement was the successful transfer of resiniferatoxin (RTX) to a private firm, which involved NIHs first, combined Orphan Drug Designation with exclusive license, execution of a Letter of Agreement forming a partnership between the Clinical Center, NINDS and NIDCR, and NIDCRs scientific, clinical, and financial support of a RTX NINDS CRADA with the licensee. Office staffs efforts to alert management of significant over-obligations in the patent expenses within the technology transfer budget has had positive ramifications: the NIH Office of Technology Transfer is developing metrics that monitor de-obligations and is communicating with License and Patent Managers to identify ways to reduce unnecessary over-obligations. Due to the increased workload due to heavy use of technology transfer services and improved oversight from newly implemented NIH and NIDCR material transfer policies, the technology transfer office filled a full-time Technology Development Specialist position in FY2011.