COBRE: RIH:CORE A: ADMINISTRATION & CAREER DVMT

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 CCRD的使命是基于导致胃肠道癌症的细胞和分子途径的原始、协作、多学科实验室研究，创造、解释和应用新知识。 这一广泛的研究领域由研究人员进行与四个主要主题相关的研究-主题A -胎儿蛋白质和表型在癌症中的意义;主题B -胃肠道肿瘤的发病机制;主题C -与致癌相关的信号转导机制;主题D -RNA和DNA病毒在癌症中的作用。 该中心由外部咨询委员会（EAC）提供咨询，该委员会包括5位杰出的科学家：丹尼尔弗林博士（西弗吉尼亚州COBRE信号转导和癌症中心主席兼主任）;苏珊菲舍尔博士（医学博士安德森癌症中心）;纳尔逊福斯托博士（华盛顿大学，病理学主席）;哈里特伊森博士（宾夕法尼亚州立大学癌症研究所/ M.S. Hershey医学中心微生物学、免疫学和病理学教授）和Alan Rosmarin医学博士（血液肿瘤学部主任和马萨诸塞州大学纪念癌症中心副主任）。EAC为COBRE CCRD（也称为内部执行委员会（IEC））的领导层提供了支持。IEC包括核心董事：道格拉斯希克森博士（核心A董事）; Djuro Josic博士（核心A董事）。核心B）;罗纳德德莱利斯，医学博士（主任。Core C），Murray Resnick，MD，PhD（联合主任）核心C）;副主任，乔纳森Reichner，博士;和导师：菲利普Grupposo，医学博士;彼得Quesenberry，医学博士;和杰克魔杖，医学博士。 COBRE CCRD网站可以在http://www.lifespan.org/rih/services/cobre上找到。它列出了NCRR为该中心提供的资金。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The mission of the CCRD is to create, interpret, and apply new knowledge based on original, collaborative, multidisciplinary laboratory studies of the cellular and molecular pathways leading to gastrointestinal cancer. This broad area of research is represented by investigators pursuing research relevant to four major themes - Theme A - The significance of fetal proteins and phenotypes in Cancer; Theme B - Pathogenesis Of GI Tumors; Theme C - Signal Transduction Mechanisms Relevant to Carcinogenesis; Theme D - Role of RNA and DNA Viruses in Cancer. The center is advised by the External Advisory Committee (EAC), which includes 5 distinguished scientists: Daniel Flynn, PhD (Chair and Director of the COBRE Center for Signal Transduction and Cancer in West Virginia); Susan Fischer, PhD (MD Anderson Cancer Center); Nelson Fausto, MD (Univ. of Wash., Chair of Pathology); Harriet Isom, PhD (Penn State Cancer Inst./M.S. Hershey Med. Center Dist.Prof. Microbiolgy, Immunology and Pathology); and Alan Rosmarin, MD (Chief, Division of Hematology Oncology and Deputy Directof of University of Massachusetts Memorial Cancer Center). The EAC provided advisement to leadership of the COBRE CCRD, also known as the Internal Executive Committee (IEC). The IEC includes the Core Directors: Douglas Hixson PhD (Dir.Core A); Djuro Josic, PhD (Dir. Core B); Ronald DeLellis, MD (Dir. Core C), Murray Resnick, MD, PhD (Co-Dir. Core C); the Deputy Director, Jonathan Reichner, PhD; and the mentors: Philip Grupposo, MD; Peter Quesenberry, MD; and Jack Wands, MD. The COBRE CCRD website can be found at http://www.lifespan.org/rih/services/cobre. It lists NCRR funding for this Center.