MARINE NATURAL PRODUCTS

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 总体而言，该项目将以海洋天然产品为重点。特别是，天然产物的结构将主要使用核磁共振来阐明。首要目标是分离出具有治疗潜力的新型天然产品。现代药物发现需要在少量样本上快速表征生物活性药物。因此，NMRFAM的资源对这个项目来说是无价的。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. In general, this project will focus on marine natural products. In particular, strutures of natural products will be elucidated using primarily NMR. The overarching goal is to isolate novel natural products that have therapeutic potential. Modern drug discovery requires rapid characterization of bioactive hits on small quantities of sample. Therefore, the resources at NMRFAM are invaluable to this program.