IN-VIVO DETERMINATION OF SKIN OPTICAL PROPERTIES

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 我们开发了一种扩散探头，它可以与漫反射光谱(DOS)方法结合使用，在650-1000 nm的波长范围内非侵入性地测量体内浅层皮肤的全光谱光学性质。这种新的探头依靠一个简单的两层扩散模型来确定组织的吸收和折合散射系数。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We have developed a diffusing probe, which can be used in combination with diffuse optical spectroscopic (DOS) methods, to noninvasively determine full spectrum optical properties of superficial in-vivo skin in the wavelength range from 650-1000 nm. This new probe relies on a simple two-layer diffusion model to determine tissue absorption and reduced scattering coefficients.