SOFTWARE DEVELOPMENT FOR SMALL ANGLE X-RAY SCATTERING DATA COLLECTION, BASED ON

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 对分布式控制系统（DCS）和随附的图形用户界面Blu-Ice进行了更多改进，使BL 4 -2的非晶X射线散射/衍射研究更加高效、直观和用户友好。 2010年最值得注意的改进包括：1）将Pilatus 300 K探测器纳入Blu-Ice/DCS的控制中，这使得时间分辨SAXS实验的挑战性大大降低; 2）创建新的GUI和快速高通量脂质衍射的能力（该？lipSAXS？标签），使用户能够在短时间内获得大量蛋白质的晶体学信息，以及3）基于PX软件开发人员自2007年底以来所做的改进，对Blu-Ice和DCS进行了重大升级，使软件更加通用和安全。 还有其他许多软件改进，使光束线控制和数据收集更有效，直观和用户友好。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. More improvements to the distributed control system (DCS) and accompanying graphical user interface Blu-Ice have been implemented to make non-crystalline x-ray scattering/diffraction studies more efficient, intuitive, and user friendly at BL4-2. The most notable improvements made in 2010 include 1) incorporation of the Pilatus 300K detector into the control of Blu-Ice/DCS, which makes time resolved SAXS experiements much less challenging; 2) creation of new GUI and capabilities for rapid high throughput lipid diffraction (the ?lipSAXS? tab), which allows the user to obtain crystallographic information of a large number of proteins in a short period of time, and 3) major upgrades to Blu-Ice and DCS based on the improvements made by the PX software developers since late 2007, which makes the software more versatile and secure. There are also other numerous software improvements that make beam line control and data collection more efficient, intuitive, and user friendly.