ALCOHOL EFFECTS ON THE ADOLESCENT BRAIN

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 该项目正在进行中，其目的是使用纵向双胞胎对照设计研究48对同卵双胞胎，以评估酒精和药物使用对大脑结构和功能的影响。该项目使用了一套全面的、互补的神经心理学、心理生理学和MRI评估方法。MRI成像包括用于形态测量分析的高分辨率结构成像和在表现出对奖励敏感的神经区域敏感的任务期间的全脑功能成像。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. he purpose of the project, which is ongoing, is to study 48 pairs of monozygotic twins using a longitudinal cotwin-control design to assess effects of alcohol and drug use on brain structure and function. The project uses a comprehensive and complementary battery of neuropsychological, psychophysiological and MRI assessment. MRI imaging includes high-resolution structural imaging for morphometric analyses and whole-brain functional imaging during performance of a task shown to be sensitive to reward-sensitive neural areas.