ADMINISTRATION

项目总结（见说明）： 该项目的中心主题是研究人类膝关节的老化及其与骨关节炎（OA）的关系。行政核心将把核心和项目的努力集中在这一主题上，提出假设和研究方向，并确定科学进展。该核心将为最有效地利用资源提供行政支助。核心将保持访问不同的 我们的工作是收集膝关节和软骨的样品，并通过岩心监测样品处理和项目分析。核心A还作为数据管理的中心单元，并维护项目中研究的所有膝关节样本的数据库。行政核心的具体目标是： 目标1。监测各个项目的科学进展。 目标二。促进项目中研究者之间的互动。 目标3。支持青年科学家和开发新项目。 目标4。提供膝关节和软骨样本。 目标5。维护中央数据库。 目标6。进行统计分析。 目标7。协调项目的所有财务活动。 目标8。确定负责任的研究行为。 瞄准9执行危险材料工作的安全措施。 目标10将组织和组织提取物分发给外部研究者。

PROJECT SUMMARY (See instructions): The central theme of this program is to study aging of the human knee joint and its relationship to osteoarthritis (OA). The Administrative Core will focus efforts of the cores and projects on this theme, advance hypotheses and research directions and ascertain scientific progress. The core will provide administrative support for the most efficient utilization of resources. The core will maintain access to different sources of knee joints and cartilage and monitor sample processing by the cores and analysis by the projects. Core A also serves as the central unit for data management and maintains the database for all knee specimens that are studied in the program. The Specific Aims of the Administrative Core are: Aim 1. Monitor scientific progress in the individual projects. Aim 2. Promote interactions among the investigators in the program. Aim 3. Support young scientists and development of new projects. Aim 4. Provide access to knees and cartilage samples. Aim 5. Maintain central database. Aim 6. Perform statistical analysis. Aim 7. Coordinate all fiscal activities of the program. Aim 8. Ascertain responsible conduct of research. Aim 9. Enforce safety measures for work with hazardous materials. Aim 10. Distribute tissues and tissue extracts to outside investigators.