Biostatics

马约诊所癌症中心（MCCC）的生物统计学共享资源（BSR）提供了专家 与MCCC研究人员合作超过35年。目的是提供统计和 生物数学合作的发展和同行评议的癌症研究产生的行为 MCCC的调查人员。研究包括基础科学，临床试验，流行病学研究， 其他翻译和教育研究。CCSG资金的主要用途是支持统计和 在试点项目上进行生物数学合作，以协助研究人员开发经批准的 研究项目没有其他资助，但导致外部资金，并支持意外 需要在MCCC批准的项目上进行统计合作。在其历史上，BSR经历了 自然和故意的演变和扩展，由MCCC不断扩大的研究活动所推动。 在当前的资助期内，BSR在两个主要领域成功地进行了战略性扩张： 三维基因组和蛋白质组数据分析（4个新的教师与此专业知识），并向所有3个MCCC 校园。BSR教师实际上位于所有3 MCCC校园，整个资源 通过多种机制定期有效沟通，确保协调协作。 BSR将多个重点领域（团队）结合在一起，形成一个组织良好、高效的核心。它们是：（一） 临床试验团队，负责癌症临床试验、相关转化研究、干预性研究 心理社会研究，病人和公众教育研究项目，（二）人口科学小组 负责为癌症观察提供统计协作和数据管理支持， 研究，包括遗传和分子流行病学，（三）生活质量小组负责提供 一般和具体的合作，测量工具和分析，为MCCC调查人员调查 临床和心理社会干预对癌症患者、家庭、护理人员和其他人的影响，以及 (IV)一个生物数学团队，提供成像数学方面的协作专业知识， 数据处理和分析，疾病过程的数学建模，以及一般的数学或 算法问题。BSR为MCCC研究人员提供统计和生物数学合作 所有三个MCCC校园。该资源非常富有成效，有528名同行评审 出版物，并在104个NIH或NIH同等赠款中进行了合作。 目前的补助期。

The Biostatistics Shared Resource (BSR) of the Mayo Clinic Cancer Center (MCCC) has provided expert statistical collaboration with MCCC investigators for over 35 years. The purpose is to provide statistical and biomathematical collaboration for the development and conduct of peer-reviewed cancer research generated by MCCC investigators. Research encompasses basic science, clinical trials, epidemiologic research, and other translational and educational research. The primary usage of CCSG funds is to support statistical and biomathematical collaboration on pilot projects, for assistance to investigators in developing approved research projects not otherwise funded but leading towards external funding, and to support unanticipated needs for statistical collaboration on MCCC approved projects. Over its history the BSR has undergone a natural and deliberate evolution and expansion, spurred by the expanding research activities of the MCCC. In the current grant period the BSR has successfully and strategically expanded in two primary areas: high dimensional genomic and proteomic data analysis (4 new faculty with this expertise), and to all 3 MCCC campuses. BSR faculty are physically located on all 3 MCCC campuses, and the entire resource communicates regularly and effectively through multiple mechanisms to ensure coordinated collaboration. The BSR has multiple focus areas (teams) tied together into a well-organized, efficient core. These are: (I) a Clinical Trials team responsible for cancer clinical trials, associated translational research, interventional psychosocial research, and patient and public education research projects, (II) a Population Science team responsible for providing statistical collaboration and data management support for cancer observational studies, including genetic and molecular epidemiology, (III) a Quality of Life team responsible for providing general and specific collaboration, measurement tools, and analysis for MCCC investigators investigating the impact of clinical and psychosocial interventions on cancer patients, families, caregivers, and others, and (IV) a Biomathematics team that provides collaborative expertise in the mathematical aspects of imaging, data processing and analysis, mathematical modeling of diease processes, and general mathematical or algorithmic issues. The BSR provides statistical and biomathematical collaboration to MCCC investigators across all three MCCC campuses. The resource has been remarkably productive, with 528 peer reviewed publications in the current grant period, and has collaborated on 104 NIH or NIH equivalent grants in the current grant period.