ISU-Vet-LRN Cooperative Agreement Proposal

项目总结 拟议的工作是为了爱荷华州立大学兽医诊断公司之间的合作协议 实验室(ISU VDL)和FDA兽医中心Vet-LRN在三个领域提供支持： A)在发生大规模动物疾病时为诊断目的对兽医诊断样本进行测试。 样品可以是动物性食品/饲料/药品和与饲料/食品/药品生产有关的环境样品。 和/或联邦、州和地方机构根据以下条款收集的动物诊断尸检或临床样本 协调FDA VPO；b)为监管目的提供分析支持，包括能力测试，以 提高兽医诊断实验室检测结果的质量；以及c)参与方法 开发和验证，以及矩阵扩展。 ISU VDL是由AAVLD认证的全方位服务实验室，提供尖端诊断 为爱荷华州及其他地区提供服务。ISU VDL的病例装载在全国是独一无二的，因为它是 主要是与食用动物有关的。实验室不仅是食品安全领域的第一道防线 给全国各地的食用动物生产者，也大力从事保护宠物动物健康的工作。这 该项目将具体解决与导致动物疾病或死亡的化学污染有关的问题。 我们的大量食用动物产品出口到海外的欧盟和亚洲，这两个市场 对食品安全敏感。参与这一合作协议计划也将使FDA、实验室 和爱荷华州，因为这个项目的所有方面都为我们的产品增加了价值-即及时和可靠 结果。 ISU VDL装备齐全，人员配备齐全，能够积极影响FDA的需求，正如FOA中所概述的那样。 具体地说，我们有必要的基础设施来快速准确地诊断中毒使用 动物或环境样本，并协助FDA开发和验证基于组织或 动物药。作为粮食应急网络的成员和长期参与者 (FERN)作为VET-LRN的创始成员，我们拥有准确报告结果的基础设施 而且效率很高。我们工作产品的质量由一个独立的质量保证单位监督。在……里面 总而言之，我们有资源和基础设施来及时交付我们的工作成果。

PROJECT SUMMARY The proposed work is for a cooperative agreement between Iowa State University Veterinary Diagnostic Laboratory (ISU VDL) and the FDA Center for Veterinary Medicine Vet-LRN to provide support in three areas: a) testing of veterinary diagnostic samples in the event of large scale animal illnesses for diagnostic purposes. The samples could be animal food/feed/drugs and environmental samples related to feed/food/drug production and/or animal diagnostic necropsy or clinical samples collected by Federal, State, and Local agencies under the coordination of the FDA VPO; b) analytical support for regulatory purposes, including proficiency testing to enhance the quality of test results from veterinary diagnostic laboratories; and c) participation in method development and validation, and matrix extension. The ISU VDL is a full service fully accredited laboratory by the AAVLD which provides cutting edge diagnostic services to the State of Iowa and beyond. The case load at the ISU VDL is unique in the nation because it is predominantly food-animal related. The laboratory is not only the first line of defense in the area of food safety to food animal producers across the country, but also heavily engaged in protection of pet animal health. This project will specifically address issues related to chemical contamination leading to animal illnesses or death. A significant amount of our food animal products are exported overseas to the EU and Asia, markets that are sensitive to food safety. Participation in this cooperative agreement program will also benefit the FDA, the lab and the State of Iowa as all aspects of this project add value to our product-namely, timely and reliable results. The ISU VDL is well equipped and staffed to positively impact the needs of the FDA as outlined in the FOA. Specifically, we have the necessary infrastructure to quickly and accurately diagnose intoxications using animal or environmental samples, and to assist the FDA to develop and validate new tests based on tissues or animal medications. As members and long-term participants in the Food Emergency Response Network (FERN) and also as founding members of Vet-LRN, we have the infrastructure to report out results accurately and efficiently. The quality of our work product is overseen by an independent Quality Assurance Unit. In summary, we have the resources and infrastructure to deliver our work product in a timely manner.