Geriatric Oncology Research to Improve Clinical Care

描述(由申请人提供)：这是一项为期五年的U13合作会议拨款的初步申请，题为“老年肿瘤学研究以改善临床护理”，代表癌症和老龄研究小组(CAIG)与国家老龄研究所(NIA)和国家癌症研究所(NCI)老年病学和临床老年学分会合作提交。这一会议资助计划的任务是为老年病学和肿瘤学的多学科研究团队提供一个论坛，以审查老年肿瘤学的现有证据水平，确定最优先研究的领域，并开发研究方法，以在未来10年内改善患有癌症的老年人的临床护理。随着美国人口迅速老龄化，需要癌症治疗的老年人数量也急剧增加；然而，在设定肿瘤护理标准的临床试验中，这一不断增长的人口的代表性仍然不足。有必要制定一项研究议程，最大限度地发挥老年病学和肿瘤学之间的协同作用，确定最优先研究的领域，并改进研究方法，以加强这两个领域之间的合作。这项会议拨款的目标是：1.确定老年肿瘤学目前的证据水平和高度优先的研究领域2.从老年病学和肿瘤学领域确定研究方法上的优势，可以应用并整合到涉及患有癌症的老年人的研究中3.促进多学科学术团队之间的合作，重点是在老年肿瘤学研究中使用共同的研究方法4.促进和促进老年肿瘤学现有和新的研究人员的研究5.传播本会议拨款计划的成果和易于适应的建议，以加强老年肿瘤学研究方法论。相关会议系列的建议议题包括：1。老龄化与癌症研究的生物学、临床和心理社会关联。2.设计和实施治疗老年和/或体弱成人癌症的临床试验。3.设计和实施干预研究，以维持或提高老年和/或体弱成人癌症患者的生存质量。这三个拟议的会议将相互促进，最初的会议有助于微调后续会议的程序和结构。该系列会议将由一个监督委员会领导，该委员会由来自NIA、NCI和CAG以及其他致力于老年学和/或肿瘤学的组织(AGS、ASCO、SIOG、AACR)的成员组成。每一次会议都将有一个方案委员会，负责与每一次会议主题有关的内容和进程，负责会议的交付和成果的传播。

DESCRIPTION (provided by applicant): This is an initial application for a five-year U13 cooperative conference grant titled "Geriatric Oncology Research to Improve Clinical Care", submitted on behalf of the Cancer and Aging Research Group (CARG) in collaboration with the Geriatrics and Clinical Gerontology branch of the National Institute on Aging (NIA) and the National Cancer Institute (NCI). The mission of this conference grant program is to provide a forum for a multidisciplinary team of investigators in geriatrics and oncology to review the present level of evidence in geriatric oncology, identify areas of highest research priority, and develop research approaches to improve clinical care for older adults with cancer within the next 10 years. As the US population rapidly ages, the number of older adults needing cancer treatment also increases dramatically; however, this growing population continues to be underrepresented in clinical trials that set the standards for oncology care. There is a need to develop a research agenda that maximizes the synergy between geriatrics and oncology, to identify areas of highest research priority, and to refine research approaches that enhance collaboration between both fields. The goals of this conference grant are: 1. To identify the present level of evidence and areas of high research priority in geriatric oncology 2. To identify strengths in research methodology, from the fields of geriatrics and oncology, that can be applied and integrated into research studies involving older adults with cancer 3. To foster collaboration between multidisciplinary scholarly teams, with a focus on shared research methods to be utilized across studies in geriatric oncology 4. To foster and promote the research of existing and new investigators in geriatric oncology 5. To disseminate findings from this conference grant program with easily adaptable recommendations to strengthen geriatric oncology research methodology. Proposed topics for the linked conference series include: 1. Biological, Clinical, and Psychosocial Correlates at the Interface of Aging and Cancer Research. 2. Design and Implementation of Therapeutic Clinical Trials for Older and/or Frail Adults with Cancer. 3. Design and Implementation of Intervention Studies to Maintain or Improve the Quality of Survival of Older and/or Frail Adults with Cancer. These three proposed conferences will build upon one another, with initial meetings helping to fine-tune the program and structure of subsequent meetings. The conference series will be led by an Oversight Board consisting of members from the NIA, NCI, and CARG, as well as other organizations dedicated to geriatrics and/or oncology (AGS, ASCO, SIOG, AACR). Each conference will have a Program Committee that will be responsible for content and processes related to the topic of each conference, for delivery of the conference, and dissemination of the findings.