女性药物滥用障碍治疗的身体导向疗法-猫眼课题宝

女性药物滥用障碍治疗的身体导向疗法

批准号：

8437077

负责人：

CYNTHIA J PRICE

金额：

$50.84万

依托单位：

UNIVERSITY OF WASHINGTON

依托单位国家：

美国

项目类别：

财政年份：

2013

资助国家：

美国

项目状态：

已结题

起止时间：

2013-09-15 至 2017-06-30

来源：

https://reporter.nih.gov/project-details/8437077

关键词：

Address Affect Aftercare Alcohol dependence Alcohol or Other Drugs use Alcohols Attention Awareness Behavior Control Behavioral Beryllium Biological Markers Brain Clinical Research Communities Dependence Disease Dissociation Drug Addiction Drug usage Economics Education Effectiveness Emotional Employment Enrollment Female Funding Gender Goals Health Health education Illicit Drugs Imprisonment Individual Institute of Medicine (U.S.)Learning Legal Longitudinal Studies Manuals Measures Mediating Mediator of activation protein Medical Mental Health Mind-Body Intervention National Institute of Drug Abuse Outcome Outpatients Patient Self-Report Patients Process Psychophysiology Public Health Randomized Randomized Clinical Trials Recruitment Activity Regulation Relapse Reporting Research Risk Self Care Sensory Societies Staging Strategic Planning Stress Stroke Substance Use Disorder Surveys Testing Therapeutic Intervention Time Training Trauma Treatment Efficacy Treatment outcome United States National Institutes of Health Woman Women&apos s Health addiction aged base body-mind cost design disorder later incidence prevention drug addict economic outcome efficacy testing emotion regulation follow-up improved innovation meetings men mindfulness novel physical conditioning post intervention prevent programs public health relevance reduced substance use sex skills substance abuse treatment therapy development tool treatment as usual

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中文摘要

翻译

描述(申请人提供)：这项研究的长期目标是改善女性物质使用障碍(SUD)的治疗。近期的项目目标是测试一种创新的身心干预措施--身体导向疗法中的正念意识(MABT)的有效性，以减少SUD治疗中女性的药物使用复发。MABT是一种新颖的心身方法，它将动手(手动)方法与心身心理教育方法相结合，即互感训练和正念，以发展基于身体的自我护理技能，并促进情绪调节。这是一项使用重复措施的三组随机临床试验，该项目将招募225名妇女并将其随机分成三组：MABT+照常治疗(TAU)(n=75)、仅TAU(n=75)和妇女健康教育(WHE)+TAU(以控制时间和注意力)(n=75)。研究条件将在基线、干预后以及6个月和12个月的随访时进行比较。主要目的是验证这样的假设，即与TAU和WHE+TAU相比，MABT在12个月的随访中将导致物质使用和相关的健康结果减少。第二个目标是检验假设的MABT的潜在机制。第三个目标是探索一种相互感觉的生物标志物作为治疗结果的预测因子。在两个不同的社区治疗设施中服务于不同种族患者的女性门诊患者将被招募参加研究。这项研究建立在MABT在女性物质使用障碍治疗中的可行性和可接受性的有希望的初步证据的基础上，并解决了旨在改善女性SUD治疗结果的更多临床研究的必要性。

英文摘要

DESCRIPTION (provided by applicant): The long-term objective of this study is to improve women's substance use disorder (SUD) treatment. The immediate project goal is to test the efficacy of an innovative mind-body intervention, Mindful Awareness in Body-Oriented Therapy (MABT) to reduce substance use relapse among women in SUD treatment. A novel mind-body approach, MABT combines a hands-on (manual) approach with mind-body psycho-education approaches of interoceptive training and mindfulness to develop somatically-based self-care skills and to facilitate emotion regulation. A three-group, randomized clinical trial using repeate measures, this project will enroll and randomize 225 women to one of three groups, MABT + Treatment-as-usual (TAU) (n=75), TAU only (n=75), and Women's Health Education (WHE) + TAU (to control for time and attention) (n=75). Study conditions will be compared at baseline, post-intervention, and at 6 and 12 month follow-up. The primary aim is to test the hypothesis that MABT will result in reduced substance use and related health outcomes compared to TAU and to WHE+ TAU at 12 month follow-up. The second aim is to examine hypothesized underlying mechanisms of MABT. The third aim is to explore an interoceptive biomarker as a predictor of treatment outcome. Female outpatients in two diverse community treatment facilities, serving racially diverse patients, will be recruited for study participation. This stud builds on promising preliminary evidence of MABT feasibility and acceptability in substance use disorder treatment for women, and addresses the need for more clinical research aimed at improving SUD treatment outcomes for women.

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