The Cognitive Mechanisms of Mindful Attention and Stress

压力与心脏病、抑郁、焦虑、糖尿病和免疫功能抑制的风险增加有关。虽然几十年的研究已经探索了生物化学组成和对压力事件进行分类的过程，但压力思维背后的特定认知机制还没有得到很好的理解。从长远来看，了解这些机制将有助于如何测量，治疗和缓解压力。 先前的研究已经解决了可能导致事件体验为压力的认知机制;即，个体变得如此沉浸在压力思想的心理重演中，以至于思想本身引发了压力反应和负面情绪。正念注意力可以防止个人沉浸在压力思想的体验中并引发压力反应。正念注意力包括认识到一个人的思想是存在于一个人的头脑中的精神状态，而不是在外部世界。当一个人以这种方式对待思想时，它们会在没有压力反应的情况下产生和消散。目前，人们对如何通过正念注意力来防止沉浸在紧张的思想中减少个体对压力的主观体验及其神经实现缺乏了解。 在一项功能性磁共振成像研究中，本研究旨在填补这一空白，通过比较参与者完全沉浸在对压力情景的思考中（沉浸视角）时的神经活动，以及他们将自己的想法视为短暂的精神状态（正念视角）时的神经活动。这将有助于揭示认知机制，有助于在思想中重现压力事件。研究人员还将研究减少沉浸在压力思想中的神经基础。此外，研究人员还将研究特质吸收、沉思和正念的个体差异如何影响沉浸在压力思维中的倾向。那些更容易沉思或吸收能力更高的参与者，与那些天生专注力高的人相比，可能在正念注意力方面遇到更多困难。该项目的结果将增加我们对如何对抗压力的负面影响，如何治疗与压力有关的疾病以及如何识别有压力相关疾病风险的人的理解，从而有可能进行预防。这项工作也可能揭示正念注意力的神经机制，以及为什么正念相关治疗具有治疗效果。

Stress is linked to increased risk of heart disease, depression, anxiety, diabetes, and suppressed immune function. Though decades of research have explored the biochemical makeup and the process of categorizing a stressful event, the specific cognitive mechanisms underlying stressful thoughts are not well understood. In the long run, understanding these mechanisms will inform how to measure, treat and ameliorate stress. Previous research has addressed cognitive mechanisms that may contribute to the experience of an event as stressful; namely, individuals become so immersed in the mental reenactment of stressful thoughts that the thought itself triggers a stress response and negative emotion. Mindful attention can prevent individuals from becoming immersed in the experience of stressful thoughts and setting off a stress response. Mindful attention involves recognizing one's thoughts are mental states that exist in one's mind, but not in the external world. When one treats thoughts this way, they arise and dissipate without a stress response. Currently, there is a lack of understanding about how preventing immersion in stressful thoughts through mindful attention reduces the individual's subjective experience of stress and its neural implementation. In an fMRI study, the present research aims to fill this gap by comparing neural activity when participants are fully absorbed in their thoughts about stressful scenarios (immersion perspective) to periods when they observe their thoughts as fleeting mental states (mindful perspective). This will shed light on cognitive mechanisms that contribute to mentally reenacting stressful events in thought. Researchers will also examine the neural underpinnings of reducing immersion in stressful thoughts. In addition, researchers will investigate how individual differences in trait absorption, rumination and mindfulness affect the tendency to become immersed in stressful thought. Participants who are more likely to ruminate or are higher in absorption may have more difficulty with mindful attention compared to those naturally high in mindfulness. Results of this project will increase our understanding of how to combat the negative effects of stress, how to treat stress related disorders, and how to identify persons at risk for stress related ailments, thereby potentially enabling prevention. This work may also shed light on the neural mechanisms of mindful attention and why there is a therapeutic effect of mindfulness-related treatments.