Cincinnati Regional Coordinating Stroke Center (Cincinnati RCC)

描述（由申请人提供）：拟议的NINDS卒中临床试验网络（NINDS）的目标是利用多学科卒中专业知识，在所有阶段协同有效地设计和执行卒中临床试验。我们将带来一个完全整合的临床试验网络方法，以更广泛和更有凝聚力的中风作为区域协调中心（RCC）的NATIONAL。我们的目标是（1）有效地实施试验，招募和留住参与者，并作为RCC优化数据质量，（2）作为经验丰富的科学家，临床医生，试验者和协调员积极参与NATIONAL，以及（3）成功培训 下一代中风临床试验者。我们将通过带来经验丰富的领导，接触不同的患者群体，建立研究基础设施和支持性管理来实现这些目标。我们的机构已通过同意使用标准化的主试验协议、采用集中的IRB审查并提供额外的机构资金来支持RCC学员，表明了他们对NRC的承诺。我们计划成为NATIONAL的关键合作伙伴，通过高质量的中风试验为我们的患者带来最具临床影响力的中风治疗。

DESCRIPTION (provided by applicant): The objectives of the proposed NINDS Stroke Clinical Trials Network (NSTN) are to harness multidisciplinary stroke expertise to collaboratively and efficiently design and execute stroke clinical trials in all phases. We will bring a fully integratd clinical trial network approach to stroke more broadly and cohesively as a Regional Coordinating Center (RCC) of the NSTN. Our goals are to (1) efficiently implement trials, recruit and retain participants, and optimize data quality as an RCC, (2) actively participate in the NSTN as experienced scientists, clinicians, trialists, and coordinators, and (3) successfully train the next generation of stroke clinical trialists. We will achieve these goals by bringing experienced leadership, access to a diverse patient population, an established research infrastructure, and a supportive administration. Our institution has shown their commitment to the NSTN by agreeing to use a standardized Master Trial Agreement, employ a centralized IRB review, and provide additional institutional funds to support the RCC trainee. We propose to be a key partner in the NSTN working to bring the most clinically impactful stroke therapies to our patients through high-quality stroke trials.