Healthy Children for a Healthy Future (HC4HF):A Collaborative Health Disp. Res.*

描述(由申请人提供)：在各种暴露、条件、疾病和治疗中，儿童的健康方面存在着有据可查的、普遍存在的、不可接受的种族和民族差异。这种差距不仅直接给儿童本身、他们的家庭和社区带来负担，而且还会对几代人产生长期影响。华盛顿特区-巴尔的摩地区的特点是严重的收入不平等、居住隔离和儿童健康方面的显著差异。此续签申请建立了健康儿童健康未来：卓越合作健康差异研究中心(HC4HF)，并建立在霍华德大学(HU)、儿童国家医学中心(CNMC)和约翰霍普金斯大学(JH)儿科在DC-巴尔的摩儿童健康差异研究中心下对儿童健康差异研究和培训的长期合作承诺的基础上。我们的工作纳入了儿童健康差距的概念模型和寿命视角，并专门致力于制定干预措施，以克服儿童健康差距。儿童基金会的总体目标是为华盛顿特区-巴尔的摩地区旨在改善少数族裔儿童健康和克服儿童健康差距的高效和有效的研究、培训和社区参与提供一个广泛合作、多学科和多机构的“家”。为了实现这一总体目标，我们解决了以下具体目标：1)实施一项严格的干预研究计划，以优化青春期关键发育期的健康，将早期接触与长期的成人和代际健康联系起来。这项工作将利用“移动健康”(m-Health)领域的新兴技术，如短信，以测试针对两种高度相关的疾病的干预措施，这些疾病对城市非裔美国青少年的影响不成比例(2型糖尿病风险/肥胖和暴力暴露)；2)培训和指导初级教员，掌握进行与少数族裔健康和健康差距相关的严格研究所需的临床和翻译研究技能；3)通过在审查和评估地理位置的健康指标的基础上提供创新的对话计划，加强华盛顿特区-巴尔的摩地区的双向社区参与和外联；并将社区咨询过程纳入培训；4)：领导一个基础广泛、多学科、多机构和协作的财团，以协调和加强与华盛顿特区-巴尔的摩地区和全国的儿童少数群体健康和健康差距有关的研究和培训。

DESCRIPTION (provided by applicant): There are well-documented, pervasive, and unacceptable racial and ethnic disparities in the health of children across a variety of exposures,conditions, diseases, and treatments. Such disparities not only directly burden children themselves, their families, and their communities, but also have long-term effects across multiple generations. The Washington, DC-Baltimore region is characterized by significant income inequality, residential segregation, and marked disparities in child health. This renewal application establishes the Healthy Children for a Healthy Future: a Collaborative Health Disparities Research Center of Excellence (HC4HF) and builds on the long-standing collaborative commitment of Howard University (HU), Children's National Medical Center (CNMC), and the Department of Pediatrics at Johns Hopkins (JH) to child health disparities research and training under the DC-Baltimore Research Center on Child Health Disparities. Our work incorporates a conceptual model of child health disparities and a lifespan perspective and Is specifically committed to the development of interventions to overcome child health disparities. The overall goal of HC4HF is to provide a broadly collaborative, multi-disciplinary and multi-institutional "home" for efficient and effective research, training, and community engagement designed to improve minority child health and overcome child health disparities in the Washington DC-Baltimore region. To achieve this overall goal, we address the following Specific Aims: 1): To implement a program of rigorous intervention research to optimize health during the critical developmental period of adolescence, which links early exposures to long-term adult and intergenerational health. This work will draw on emerging technologies in "mobile health" (m-health), such as text messaging, to test interventions targeting two highly relevant conditions disproportionately affecting urban African American adolescents (Type 2 diabetes risk/obesity and violence exposure); 2) To train and mentor junior faculty in the required clinical and translational research skills required to conduct rigorous research relevant to minority health and health disparities; 3) To strengthen bidirectional community engagement and outreach in the Washington, DC-Baltimore region by providing an innovative program of dialogue based on review and evaluation of geo-located health indicators; and by integrating the community advisory process into training; 4): To lead a broadly based, multi-disciplinary, multi- institutional, and collaborative consortium to coordinate and strengthen research and training relevant to child minority health and health disparities in the Washington, DC-Baltimore region and nationally.