Training in Neural Injury and Plasticity

描述（由申请人提供）：项目摘要/摘要这是一个在神经损伤和可塑性（NIP）的机构培训补助金的竞争性续期申请。我们请求支持4名高级博士生，他们将接受乔治敦大学神经损伤和恢复中心（CNIR）教师对神经损伤和可塑性研究的培训。该培训计划的目的是让科学家准备好研究创伤，中风或神经退行性过程引起的神经损伤的基本机制，并了解神经可塑性的基本机制，这些机制可能在功能上有利于神经损伤后的修复过程。我们的目标是培养研究人员谁将B有能力并致力于开发新的和有效的治疗策略，以减少由神经损伤导致的功能障碍的基础科学组成部分。一个经验丰富，资金充足的27名教师组成的小组，在神经损伤和可塑性方面具有广泛的研究兴趣和专业知识，将参加博士学位。培训计划。学生将通过乔治敦大学神经科学跨学科项目（IPN）进入研究生院。在头两年，他们将参加课程工作，并通过潜在导师的实验室轮换。那些对NIP计划感兴趣的人将参加一个或多个具体相关的课程，开始参加NIP期刊俱乐部，并与一群杰出的临床医生-科学家一起获得临床经验， 基础科学家与患者和临床医生处理神经损伤和可塑性的经验的赞赏。在第二年，学生将正式申请NIP培训计划，并提交由NIP培训学院的潜在导师或共同导师批准的论文研究计划大纲。作为NIP学员，他们将参加每周的NIP期刊俱乐部以及CNIR的教育计划，并计划在年度学生研讨会上报告他们的研究结果，在国家会议上发表演讲，并在同行评审的期刊上发表文章。在公共卫生方面，该计划将培养一批神经科学家，他们将接受研究和/或研究计划管理方面的培训，通过这些培训，可以治疗神经系统急性和退行性疾病的新的和更有效的治疗方法。

DESCRIPTION (provided by applicant): Project Summary/Abstract This is an application for the competitive renewal of an Institutional Training Grant in Neural Injury and Plasticity (NIP). We request support for 4 advanced predoctoral students who will be trained in research on neural injury and plasticity by faculty participating in the Center for Neural Injury and Recovery (CNIR) at Georgetown University. The purpose of this training program is to prepare scientists to investigate fundamental mechanisms of neural injury, by trauma, stroke or neurodegenerative processes and to understand basic mechanisms of neural plasticity that may be functionally beneficial to the repair processes after neural injury. Our goal is to train researchers who will b capable of and committed to the basic science component of developing novel and effective treatment strategies to reduce the functional impairments that result from neural injury. An experienced and well-funded group of 27 faculty members with a wide range of research interests and expertise in neural injury and plasticity will participate in the Ph.D. training program. Students will enter graduate school through the Georgetown University Interdisciplinary Program in Neuroscience (IPN). In the first two years they will take course work and rotate through the laboratories of potential mentors. Those interested in the NIP Program will take one or more specifically relevant courses, begin to participate in the NIP Journal Club and also obtain a clinical experience with an outstanding group of clinician-scientists, to provide basic scientists with an appreciation of the experiences of patients and clinicians dealing with neural injury and plasticity. In the second year, students will formally apply to the NIP Training Program with the outline of a thesis research proposal approved by a potential mentor or co-mentors from the NIP Training Faculty. As NIP Trainees they will participate in the weekly NIP Journal Club as well as educational programs of the CNIR and plan to report results from their research in yearly student seminars, presentations at national meetings and as publications in peer reviewed journals. With respect to public health, this program will create a cadre of neuroscientists trained for research and/or management of research programs, through which new and more effective treatments for acute and degenerative disorders of the nervous system can be treated.