Retinal Degeneration Conference

本申请是为支持第XVth视网膜变性国际研讨会而申请的资金 (RD2012)将于2012年7月16日至21日在德国巴伐利亚州巴德格宁举行。这次会议是 国际眼科研究学会(ISER)第二十九届双年度会议将于#年#月在德国柏林举行 2012年22月27日。RD2012会议将重点讨论先天免疫和后天免疫在人类免疫中的作用 视网膜退行性疾病的发生和发展。最近的研究发现，基因突变 与免疫系统的调节有关，特别是先天免疫，负责75%的年龄- 相关性黄斑变性(AMD)表明免疫系统在该病中起着重要作用。 事实上，人们越来越多地认识到免疫系统在许多形式的视网膜中的积极参与 退化，要么是主要原因，就像大多数形式的AMD似乎是这样，要么是在 发生在许多早期视网膜色素变性(RP)的退行性病理阶段。 XVth视网膜变性国际研讨会的具体目标是： 1.促进20名青年调查员(包括妇女和 通过提供旅行奖项，在视网膜变性研究中的代表不足的少数群体)。 2.提供一个论坛，传播关于以下方面的最新知识进展 获得性、遗传性和年龄相关性视网膜变性的病理生理机制 新的治疗方法。 3.创造环境，促进基层医生和临床医生之间的新思想交流 科学家并为所有民族和社会的视觉科学家创造机会 会面和建立研究合作的背景 4.组织一个以免疫系统在视网膜退化中的作用为重点的项目。 所要求的资金将用于支付20名青年调查员和3名特邀全体讲师的旅费，外加一些 管理费用适中。

This application is a request for funds to support the XVth International Symposium on Retinal Degeneration (RD2012) to be held in Bad G¿gging, Bavaria, Germany July 16 - 21, 2012. This meeting is a satellite of the XXth Biennial Meeting of the International Society for Eye Research (ISER), to be held in Berlin, Germany July 22 - 27, 2012. The RD2012 meeting will be focused on the role of innate and acquired immunity in the initiation and progression of retinal degenerative diseases. The recent discovery that mutations in genes related to regulation of the immune system, specifically innate immunity, are responsible for 75% of age- related macular degeneration (AMD) demonstrates the important role the immune system plays in this disease. In fact, there is increasing recognition of the active participation of the immune system in many forms of retinal degeneration, either a primarily cause, as appears to be the case in most forms of AMD, or during the degenerative pathological stages that take place in many of the early onset forms of retinitis pigmentosa (RP). The Specific Aims of the XVth International Symposium on Retinal Degeneration are: 1. To enhance the emerging careers of 20 young investigators (including women and underrepresented minorities) in retinal degeneration research by providing travel awards. 2. To provide a forum for dissemination of the most recent advances in the state of knowledge on the pathophysiologic mechanisms of acquired, inherited, and age-related retinal degenerations, and new therapeutic approaches. 3. To create an environment that will facilitate the exchange of novel ideas among basic and clinician scientists and generate the opportunity for vision scientists of all ethnic groups and social backgrounds to meet and establish research collaborations 4. To organize a program focused on the role of the immune system in retinal degenerations. The requested funds will support the travel of 20 young investigators and 3 invited plenary lecturers, plus some modest administrative expenses.