YALE PEDIATRIC BASIC SCIENCE TRAINING PROGRAM

描述(由申请者提供)：我们建议在耶鲁大学儿科学系发展一个基础科学培训项目。该计划的长期目标是促进内科科学家在与儿科相关的基础科学研究方面的职业发展。这一计划将建立在我们在培训内科科学家方面的丰富经验和专业知识的基础上。本申请要求每年为一名住院医师和两名医学博士或博士/博士后研究员提供博士后津贴。这一要求是基于几个因素：1)目前对致力于研究发育和儿童相关疾病的内科科学家的迫切需求。2)我们的培训人员提供的更多机会。3)申请耶鲁大学奖学金项目的人数增加。我们在研究员培训方面的经验表明，研究员需要三年或更长时间的研究培训，以发展基础科学研究所需的技能。我们相信，一个专门致力于住院医生和研究员基础科学研究的项目将导致儿科领域更多研究科学家的发展。这项计划将有几个关键组成部分：(1)为儿科住院医生建立研究课程和研究轨道。(2)招募对儿科研究有兴趣的博士后研究员。(3)将研究员与优秀的研究导师配对。(4)参与核心教学研究课程。(5)批判性和严谨的学者和项目评估。(6)建立职业指导计划。在注册该项目期间，博士后研究员将有80%的时间专门用于研究，并将提供为期3年的支持。此外，还将建立一个新的驻地研究轨道。该计划的重点将是基础科学培训，这已被确定为儿科内科科学家非常需要的领域。为了实现这些目标，我们将利用耶鲁大学专门为内科科学家培训而设立的几个项目。所有潜在的导师都得到了NIH的支持，大多数人都有经过证明的培训儿科研究员的记录。请参阅所需的T32相关支持表。表1列出了参与的部门。附录表2列出了导师和排名。附录表3列出了导师部门的培训计划。附录表4列出了导师资助支持。附录表5列出了过去10年的见习导师。附录表8列出了过去5年来申请分专业奖学金的博士后申请者。预计这一计划将培养以儿科为基础的杰出学者，他们将开始专注于与儿科相关的基础科学研究的有前途的职业生涯。

DESCRIPTION (provided by applicant): We propose the development of a basic science training program in the Department of Pediatrics at Yale University. The long-term goal of this program is to foster the career development of physician scientists in basic science research related to pediatrics. This program will build on our considerable experience and expertise in training physician-scientists. This application requests postdoctoral stipends for one resident and two MD or MD/PhD postdoctoral fellows per year. This request is based on several factors: 1) The ongoing critical need for physician scientists dedicated to studying development and childhood-related conditions. 2) The expanded opportunities afforded by our training faculty. 3) An increase in applicants to Yale fellowship programs. Our experience in fellow training indicates that three or more years of research training are needed for fellows to develop the skills needed for basic science research. We believe a program specifically dedicated to basic science research in residency and fellowship will lead to the development of additional research scientists in pediatrics. This program will have several key components: (1) Establishment of a research curriculum and research track for pediatric residents. (2) Recruitment of postdoctoral fellows with interests in pediatric research. (3) Matching fellows with superb research mentors. (4) Participation in a core didactic research curriculum. (5) Critical and rigorous Scholar and program evaluation. (6) Establishment of a career guidance program. While enrolled in the program, postdoctoral fellows will have 80% of their time specifically dedicated to research, and support will be provided for 3 years. In addition a new Resident Research Track will be established. The focus of this program will be on basic science training, which has been identified as an area where pediatric physician scientists are greatly needed. To achieve these goals, we will take advantage of several established programs at Yale specifically designed for physician scientist training. All potential mentors have NIH support and a most have a proven record of training pediatric fellows. Please see the required T32-related supporting tables. Table 1 lists participating departments. Appendix Table 2 lists mentors and rank. Appendix table 3 lists mentor department training programs. Appendix Table 4 lists mentor grant support. Appendix Table 5 lists mentor trainees over the past 10 years. Appendix Table 8 lists post-doctoral applicants for subspecialty fellowships over the past 5 years. It is anticipated that this program will lead to the training of exceptional pediatric-based Scholars, who will embark on promising careers focusing on pediatric-related basic science research.