Probiotics, Prebiotics, and the Host Microbiome: The Science of Translation

说明(申请人提供)：益生菌和益生菌在改善公共健康方面的巨大潜力在很大程度上仍未实现。由国际益生菌和益生菌科学协会和萨克勒研究所联合举办的为期一天的会议《益生菌、益生菌和宿主微生物组：翻译的科学》 将于2013年6月12日在纽约科学院举行的营养科学研讨会将探索并对我们理解益生菌和益生菌生物学的强大融合及其在人类微生物群框架中的作用产生重要而广泛的影响，从而为未来战略的制定提供信息，以将这些知识转化为创新、经济和全人群的营养和生物治疗应用，并对公众健康产生重大好处。预计将召集200名与会者，涉及广泛的科学和临床学科、细菌物种和监管/政策领域，会议将：(I)通过讲座、互动小组和联网活动，提供一个中立的论坛，讨论益生菌和益生菌生物学的当前和新兴概念，包括对人类微生物组的影响-促进通过功能食品操纵微生物组的预防和生物治疗策略的开发；(Ii)通过简短演讲、海报、奖项、旅行奖学金和折扣登记，展示职业生涯早期、女性和代表性不足的少数群体调查人员；以及(Iii)促进来自学术界、临床护理、政府和监管机构以及营养业的初级和高级代表之间的合作，以促进知识交流，从而成功地将研究转化为关于功能食品的改进的干预、治疗和政策。这次会议特别及时，因为有越来越多的强有力的科学证据支持 益生菌和益生菌，为以这一知识为基础提供了巨大的未来潜力。鉴于全球卫生保健系统面临的临床和经济挑战，如肥胖症流行和营养不良，审查这一证据以使公众、保健专业人员和政策制定者了解益生菌和益生菌作为功能食品和生物疗法的整合尤其紧迫。在主题上，会议目标与NCCAM的使命很好地一致，即通过严格的科学调查，确定补充和替代医学干预的有效性和安全性，以及它们在改善卫生保健方面的作用。纳入与肥胖、糖尿病和胃肠系统疾病相关的数据也与NIDDK的使命非常一致。在纽约科学院年鉴上发表一份持久的、开放获取的会议报告将为科学政策提供信息，并最终促进将益生菌和益生菌纳入预防和治疗多种人类疾病的保健建议中。

DESCRIPTION (provided by applicant): The great potential of prebiotics and probiotics for the improvement of public health remains largely unrealized. This one-day conference, "Probiotics, Prebiotics, and the Host Microbiome: The Science of Translation," jointly presented by the International Scientific Association for Probiotics and Prebiotics and The Sackler Institute for Nutrition Science at the New York Academy of Sciences on June 12, 2013, will explore and have important, broad impact on our understanding of the strong convergence of prebiotic and probiotic biology and its role within the human microbiome framework, thereby informing development of future strategies to translate this knowledge into innovative, economical, and population-wide nutritional and biotherapeutic applications of significant public health benefit. Anticipated to convene 200 attendees across a wide range of scientific and clinical disciplines, bacterial species, and regulatory/policy arenas, the meeting will: (i) Provide a neutral forum, through lectures, interactive panels, and networking activities, for discussing current and emerging concepts of prebiotic and probiotic biology, including the effect on the human microbiome - fostering the development of preventative and biotherapeutic strategies to manipulate the microbiome through functional foods; (ii) Showcase early career, female and underrepresented minority investigators via short talks, posters, awards, travel fellowships, and discounted registration; and (iii) Foster collaboration among junior and senior representatives from academia, clinical care, government and regulatory agencies, and the nutrition industry, to promote knowledge exchange leading to successful translation of research into improved interventions, therapies, and policy with regard to functional foods. The conference is especially timely given the increase in robust scientific evidence supporting the beneficial health effects of prebiotics and probiotics, providing great future potential to build on this knowledge. Examining this evidence in order to inform decision making by the public, health care professionals, and policymakers about the integration of prebiotics and probiotics as functional foods and biotherapeutics is particularly urgent in light of the clinical and economic challenges faced by global health care systems, such as the obesity epidemic and malnutrition. Thematically, the conference goals align well with the mission of NCCAM to define, through rigorous scientific investigation, the usefulness and safety of complementary and alternative medicine interventions and their roles in improving health and health care. The inclusion of data relating to obesity, diabetes, and disorders of the gastrointestinal system also aligns well with the mission of the NIDDK. Publication of an enduring, open-access Meeting Report in Annals of the New York Academy of Sciences will inform science policy and ultimately foster the integration of prebiotics and probiotics in health care recommendations for the prevention and treatment of a multitude of human diseases.