CCR Bioinformatics Core

CCRIFX显然满足了CCR生物信息学需求的一个关键子集，工作人员正在不断提高对CCR社区的分析支持水平。越来越明显的是，大多数研究人员大大低估了NGS分析所涉及的复杂性。CCRIFX将自己定位为NGS数据分析的中心资源。这反映在涉及核心分析的出版物数量正在增加的事实上。2011年底，核心参与了一份正在编写中的手稿。截至今年3月(2013年)，CORE正在积极地作为合著者至少撰写6篇手稿，随着研究工作的成熟，还有几篇文章出现了强大的可能性。此外，该核心作为合著者参与了4张海报，并在2份手稿中得到认可。调查人员通过服务后评估证实，CCRIFX正在帮助推进研究工作，贡献创造力和创新思维，并对未来的出版物产生有利影响。正如预期的那样，支持的测序技术强调NGS和微阵列技术。大多数请求涉及内部生成的数据。有相当多的请求需要与核心外的专家进行外部协商。ABCC和CCR生物信息学人员都在定期安排的优先顺序、状态和科学会议上提供了关键专业知识。

The CCRIFX is clearly meeting a critical subset of CCR bioinformatics needs, and the staff is continually improving the level of analysis support to the CCR community. It has become increasingly clear that most investigators have vastly underestimated the complexity involved with NGS analysis. The CCRIFX has positioned itself as the central resource for the analysis of NGS data. This is reflected in the fact that the number of publications involving the core's analysis is on the rise. At the end of 2011, the core was involved in one manuscript in development. As of March of this year (2013), the core is actively working as coauthors on at least 6 manuscripts with several more emerging as strong possibilities as research efforts mature. In addition, the core contributed as co-authors on 4 posters and was acknowledged in 2 manuscripts. Investigators have confirmed through post-service evaluations that the CCRIFX is helping to advance research efforts, contribute creativity and innovative thought as well as have a favorable impact on future publications. As expected, the sequencing technologies supported emphasize NGS as well as microarray technologies. A significant majority of requests involve data produced in-house. A substantial number of requests require external consultation with experts outside the core. Both ABCC and CCR bioinformatics personnel have provided critical expertise in regularly scheduled prioritization, status, and science meetings.