TRANS-NETWORK PROJECTS

跨网络项目的目标是引入PS-OC之外的专业知识。如果这项建议是成功的，那么我们将立即开始与以太PS-OC的工作，以创建机制，发展跨网络项目。在知道其他中心将关注什么、它们将在哪里以及它们将如何组成的情况下，很难发展这些机制。根据具体的NCI指南（http：//physics.cancer.gev/RFA/RFA-CA-09-009-FAQs.asp）和RFA，我们没有提出具体的跨网络项目，而是断言开发这些项目是我们作为中心的关键优先事项，我们期待与NCI和我们的姐妹PS-OC合作，建立一套充满活力和科学丰富的跨网络项目。例如，对我们来说，将我们的方法不仅应用于乳腺癌，而且应用于其他癌症，如前列腺癌，这将是非常重要的。理想情况下，我们将开始一个跨网络试点项目，中心集中在前列腺。我们需要做的部分工作是开发如何选择和启动跨网络试点项目的流程、机制和战略。我们已经在“中心内”试点项目部分讨论了这方面的方法。在评估进展和讨论计划的每个机会，例如在执行委员会和中心咨询委员会（CAC）的定期会议上。在中心的年度审查中，议程将包括一个具体的重点，即确定对其他专业领域的需求，扩大网络之外的互动，并使研究人员接触替代和新的方法。这一持续对话的好处之一是有机会确定可能值得开发新试点的新的科学研究方向。

The goal of the trans-network projects is to bring in expertise outside of this PS-OC. If this proposal is successful, then we will immediately begin the work with ether PS-OCs to create mechanisms for developing trans network projects. It is hard to develop these mechanisms with knowing what the other centers will focus on, where they will be, and hew they will be composed. Following the specific NCI guidance (http://physics.cancer.gev/RFA/RFA-CA-09-009-FAQs.asp) and the RFA, we do not propose specific trans-network projects, but rather assert that developing these projects is a key priority for us as a center and we look forward to working with the NCI and our sister PS-OCs to establish a vibrant and scientifically rich set of trans network projects. For example, it will be very important for us to apply our approaches net onlv to breast cancer but also to ether cancers, such as prostate cancer. Ideally, we would thus start a trans-network pilot project with a center focusing en prostate. Part of what we will need to do post-award is to develop processes, mechanisms, and strategies of how trans-network pilot projects will be selected and initiated. We have already discussed approaches for that in our 'within-center' pilot project section. At each opportunity where progress is assessed and plans are discussed, such as at regular meetings of the Executive Committee and the Center Advisory Committee (CAC). and during the Center's annual review, the agenda will include a specific focus on identifying needs for additional areas of expertise, broadening interactions beyond the network, and exposing researchers to alternative and new approaches. Among the benefits of this ongoing dialogue would be the opportunity to identify premising new lines of scientific inquiry that might merit development of new pilots.