ECOG Specimen Banking

描述（由申请人提供）：ECOG组织库是ECOG转化科学计划的重要组成部分，为ECOG成员和非成员机构的研究者提供了宝贵的资源。该申请建议继续支持这些银行的协调和运作，以收集，处理和储存高质量的标本，并使其可供研究人员用于批准的相关科学项目。ECOG将增加其高质量库存标本的营销，用于尖端研究，这反过来将改变临床护理。ECOG是NCI-Clinical Trials Cooperative Groups的集团库委员会（GBC）的积极参与者，并致力于通过ECOG在指导委员会和小组委员会中的代表与GBC合作，以实现在所有合作集团库中采集、处理、储存和分发标本的协调系统的共同目标。通用技术的使用确保了样本具有足够的质量，可用于尖端研究，便于将来自多个库的样本汇集用于大规模转化项目，并增强了跨项目比较结果的能力。通用词汇表和数据结构以及样本请求的通用策略使系统更容易为所有研究者导航，无论合作组成员身份如何。这创造了一个合议，强大和富有成效的癌症研究系统。三个主要的ECOG标本库是实体瘤库（ECOG PCO-RL）、白血病组织库和骨髓瘤组织库。每个机构都根据基于推荐的最佳实践的严格SOP，从合作组临床试验中收集和储存注释良好的标本，并遵循GBC实践，以供研究者使用。

DESCRIPTION (provided by applicant): The ECOG tissue banks are a critical part of ECOG's translational science program, providing a valuable resource to investigators at both ECOG member and non-member institutions. This application proposes continued support for the coordination and operation of these banks with the goal of collecting, processing, and storing high-quality specimens and making them available to investigators for use in approved correlative science projects. ECOG will increase the marketing of its high quality banked specimens for use in cutting edge research which in turn will change clinical care. ECOG is an active participant in the NCI-Clinical Trials Cooperative Groups' Group Banking Committee (GBC) and is committed to working with the GBC, through ECOG representation on the Steering Committee and subcommittees, toward the common goal of a harmonized system for the collection, processing, storage, and distribution of specimens across all Cooperative Group Banks. The use of common techniques ensures that samples are of sufficient quality for use in cutting edge research, facilitates pooling specimens from multiple banks for large scale translational projects, and enhances the ability to compare results across projects. Common vocabularies and data structures, as well as common policies for specimen requests, make the system easier to navigate for ail investigators regardless of cooperative group membership status. This creates a collegial, robust and productive cancer research system. The three main ECOG specimen banks are the Solid Tumor Bank (the ECOG PCO-RL), the Leukemia Tissue Bank, and the Myeloma Tissue Bank. Each collects and banks well annotated specimens from Cooperative Group clinical trials according to strict SOPs based on recommended Best Practices and follows GBC practices to make them available to investigators.