HIV Risk Among Racially-Diverse, Minority Youth: Alcohol and Partner Selection

描述（由申请人提供）：本申请要求为Stephanie Staras博士提供NIAAA指导研究科学家发展奖（K 01），以开发一项艾滋病毒预防研究计划，重点是事件级酒精使用的交叉点（即，性行为前2小时内饮酒）和少数群体青少年的性伴侣选择。为了完成从传染病流行病学到酒精相关的艾滋病毒预防的过渡，Staras博士需要保护时间来提高在青少年中制定和评估酒精相关的艾滋病毒预防干预措施的技能。Staras博士的职业发展目标是：（1）提高对青少年饮酒和艾滋病毒传播理论框架的认识;（2）加强在少数民族青少年中开展与酒精有关的艾滋病毒预防干预措施所需的研究技能;（3）提高对艾滋病毒预防研究道德行为的理解;（4）开始一项关于艾滋病毒预防的独立研究计划，重点是事件层面的酒精使用和伴侣选择。她将通过完成指导研究与导师，在课程和研讨会的参与，并指导研究完成这些目标。该研究计划开发和评估艾滋病毒预防干预措施，重点是事件级酒精使用和性伴侣选择。该研究计划有三个目标：（1）确定与无保护性行为相关的最重要的事件级酒精和伴侣特征;（2）确定风险伴侣选择和事件级酒精使用交叉的最有力的青少年风险因素;（3）开发并完成艾滋病毒预防干预的可行性试验，重点是修改青少年饮酒时的伴侣选择。在K 01的支持下，Staras博士将获得开发和评估与酒精有关的艾滋病毒预防干预措施的实践经验，并将为少数民族青年中与酒精有关的艾滋病毒预防的独立职业做好准备。 公共卫生相关性：K 01奖将为Staras博士提供受保护的时间，以过渡到与酒精相关的艾滋病毒预防干预研究的独立科学家。通过拟议的培训活动和指导研究，Staras博士将制定和实施一项艾滋病毒预防干预措施的可行性测试，重点是减少饮酒和与酒精有关的危险性性伴侣选择。

DESCRIPTION (provided by applicant): This application requests a NIAAA Mentored Research Scientist Development Award (K01) for Dr. Stephanie Staras to develop a research program of HIV prevention focused on the intersection of event-level alcohol use (i.e., alcohol use within 2 hours prior to sex) and sexual partner selection among minority adolescents. To accomplish the transition from infectious disease epidemiology to alcohol-related HIV prevention, Dr. Staras needs protected time to increase skills in developing and evaluating alcohol-related HIV preventive interventions among adolescents. Dr. Staras' career development goals are: (1) improve knowledge of theoretical frameworks for alcohol use and HIV transmission among adolescents; (2) strengthen research skills specifically needed to conduct alcohol-related HIV preventive interventions among minority adolescents; (3) increase understanding of ethical conduct of research in HIV prevention; and (4) begin an independent research program on HIV prevention focused on event-level alcohol use and partner selection. She will accomplish these goals through completion of directed studies with mentors, participation in coursework and workshops, and mentored research. The research plan develops and evaluates an HIV preventive intervention focused on event-level alcohol use and sexual partner selection. The research plan is guided by three aims: (1) identify the most important event-level alcohol and partner characteristics associated with unprotected sex; (2) identify the most potent adolescent risk factors for the intersection of risky partner selection and event-level alcohol use; (3) develop and complete a feasibility-trial of a HIV preventive intervention focusing on modifying adolescent partner selection when using alcohol. With support from this K01, Dr. Staras will gain hands-on experience in development and evaluation of alcohol-related HIV preventive interventions, and will be prepared well for an independent career in alcohol-related HIV prevention among minority youth. PUBLIC HEALTH RELEVANCE : A K01 award will provide Dr. Staras with protected time to transition into an independent scientist in alcohol related HIV preventive intervention research. Through the proposed training activities and mentored research, Dr. Staras will develop and implement a feasibility test of a HIV preventive intervention focused on reducing alcohol use and alcohol-related risky sexual partner selection.