International Research Training on TB and Other Pulmonary Complications of HIV

总结 加州大学伯克利分校（UCB）/加州大学旧金山分校（UCSF）/ 马凯雷雷大学艾滋病毒研究培训计划将支持医学科学和职业发展 马凯雷雷大学的医生、科学家、实验室技术人员和其他研究支持人员 健康科学学院（MAKCHS）。拟议的培训计划，建立在一个> 20年的历史， 在艾滋病毒/艾滋病相关研究和培训方面的合作，将针对总部设在 MAKCHS、Mulago国家转诊医院或附属非政府组织，并希望 以病人为导向的研究。目前的建议旨在增加翻译的机会， 乌干达和美国的调查人员认为，这是一个关键的代表性不足的需求。 通过在多学科环境中提供定制的教学培训和实践研究经验， 该计划将准备来自不同专业背景的个人，以促进翻译 研究团队;这种团队建设代表了一种有效和潜在的变革方法， 推进重要的、未充分研究的和固有的跨学科内容领域的研究， 艾滋病毒感染的并发症。学员将被录取在现有的硕士学位课程， MAKCHS，或在特定情况下，在授予学位的远程学习计划或个别课程 在伦敦卫生和热带医学学院或加州大学旧金山分校。选定的学员将花费有限的块， 在美国的时间在参与美国机构之一，在那里他们将进行高级课程， MAKCHS没有密集的实验室经验;接受指导，为竞争做好准备 独立的赠款资金;获得分析，解释和编写摘要的帮助， 在数据分析阶段的手稿;并受益于其他类型的职业发展和教师 辅导活动。所有学员将在进行教学的同时， 训练这些研究项目将尽可能利用正在收集的数据和标本， 通过目前在乌干达合作的NIH资助的HIV/AIDS相关研究项目收集，或建立在 这些项目的现有研究基础设施。学员将有资格竞争并获得 为他们的研究项目提供适度的资金。将优先考虑培训和研究建议， 关于翻译研究方法的获取和应用，并承诺加强多方面的研究， 学科研究团队。培训计划的结果将是增加MAKCHS的数量 教师进行高质量的，对结核病和艾滋病毒的其他肺部并发症的本地相关研究， 这反过来将有助于改善乌干达和其他高负担国家的艾滋病毒/艾滋病成果。

Summary The proposed University of California, Berkeley (UCB) / University of California, San Francisco (UCSF) / Makerere University HIV Research Training Program will support scientific and career development for medical doctors, scientists, laboratory technicians, and other research support personnel at the Makerere University College of Health Sciences (MAKCHS). The proposed training program, which builds on a > 20 year history of collaboration in HIV/AIDS-related research and training, will target junior investigators who are based at MAKCHS, Mulago National Referral Hospital, or affiliated non-governmental organizations and aspire to careers in patient-oriented research. The current proposal seeks to enhance opportunities in translational research, which has been identified by Ugandan and U.S. investigators as a critical under-represented need. By offering customized didactic training and practical research experiences in a multi-disciplinary environment, the program will prepare individuals from diverse professional backgrounds to contribute to translational research teams; this team-building represents an efficient and potentially transformative approach to advancing research in the important, under-studied, and inherently inter-disciplinary content area of pulmonary complications of HIV infection. Trainees will be enrolled either in existing masters degree programs at MAKCHS or, in selected circumstances, in degree-conferring distance-learning programs or individual courses at the London School of Hygiene and Tropical Medicine or UCSF. Selected trainees will spend limited blocks of time in the U.S. at one of the participating U.S. institutions, where they will undertake advanced courses and intensive laboratory experiences not available at MAKCHS; receive mentoring to prepare them to compete for independent grant funding; obtain assistance with analysis, interpretation, and preparation of abstracts and manuscripts at the data analysis stage; and benefit from other types of career development and faculty mentoring activities. All trainees will pursue longitudinal in-country research projects alongside their didactic training. These research projects will, whenever possible, take advantage of data and specimens being collected through current collaborative NIH-funded HIV/AIDS-related research projects in Uganda, or build on the existing research infrastructure of these projects. Trainees will be eligible to compete for and receive modest funding for their research projects. Priority will be given to training and research proposals that focus on the acquisition and application of translational research methods and that promise to strengthen multi- disciplinary research teams. The result of the training program will be an increase in the number of MAKCHS faculty conducting high quality, locally relevant research on TB and other pulmonary complications of HIV, which will in turn help improve HIV/AIDS outcomes in Uganda and other high-burden countries.