Career Development Program

黑色素瘤孢子职业发展计划(CDP)的目标是培养一支综合的各级研究人员队伍，致力于人类黑色素瘤的转化性研究。在过去的4.5年里，我们通过资助和培训了10名CDP接受者，成功地实现了这一目标，他们现在通过1个R01、1个CIDR、2个R21支持他们的黑色素瘤研究。 以及一项针对黑色素瘤的MDACC机构赠款。此外，它们还产生了大量新的数据和信息，出版了20份出版物。我们将继续这一计划，目标是(1)招聘初级和高级内科医生和基础实验室科学家，并支持他们成为黑色素瘤研究中合格的翻译研究人员；(2)提供深入的翻译科学培训 (3)教授人类黑色素瘤生物学和临床课程的基础知识，以提高获奖者进行创新转化研究的能力。M.D.独特的教育环境。 安德森和M.D.安德森黑色素瘤多学科研究计划已经并将继续确保这些目标的实现。每年最多支持3名职业发展实习生(最好是2名教员和1名博士后研究员)。NCL孢子预算的一部分(每年75,000美元) 加上M.D.安德森提供的机构承诺资金的一半(每年为CDP提供10万美元)可供孢子使用，导致每年有175,000美元用于支持黑色素瘤的CDP。 每年都会对M.D.安德森内外的合格候选人进行征集。获奖者将由孢子执行委员会和内部咨询委员会进行审查和排名，最后决定由外部咨询委员会做出。第二年的支助也将视内部咨询委员会的审查情况而定。我们的导师计划包括 提供全面培训的国家认可的临床和翻译研究人员。他们的成功从过去4.5年来获得CDP奖的科学家群体的成就中可见一斑。其中两个人现在是这个孢子的完全捐赠者，担任项目的联合负责人。 我们建议继续保持我们已经建立的高标准，并每年对我们的计划进行评估。我们将根据需要修改我们的选拔和培训程序，使我们能够在整个孢子任期内继续培训未来的科学家进行人类黑色素瘤的翻译研究。

The goal of the Melanoma SPORE Career Development Program (CDP) is to develop an integrated cadre of investigators at all levels of training dedicated to translational research on human melanoma. We have successfully accomplished this goal over the past 4.5 years of this SPORE through our funding and training of ten CDP recipients who are now supporting their melanoma research through 1 R01,1 CIDR, 2 R21s, and one MDACC Institutional grant on melanoma. In addition they have generated a substantial quantity of new data and information resulting in 20 publications. We will continue this program and aim to (1) recruit junior and senior physicians and basic laboratory scientists and support them to become competent translational investigators in the study of melanoma, (2) provide in-depth training in translational science principles of human cancer biology not commonly included in clinical fellowship training or Ph.D. programs, and (3) teach the fundamentals of the biology and clinical course of human melanoma to improve the ability of the awardees to conduct innovative translational research. The unique educational environment at M.D. Anderson and in the M.D. Anderson Melanoma Multidisciplinary Research Program has and will continue to assure that these goals are met. Up to three career development trainees (preferably 2 faculty members and 1 post doctoral fellow) will be supported annually. A portion of the NCl SPORE budget ($75,000 per year) plus half of the institutional commitment funds ($100,000 for the CDP per year) provided by the M.D. Anderson is available to the SPORE, resulting in $175,000 each year to Support the CDP in Melanoma. Solicitations will be made yearly for qualified candidates from within and outside of M.D. Anderson. The awardees will be reviewed and ranked by the SPORE Executive Committee and Internal Advisory Committee, with final decision made by the External Advisory Committee. A second year of support will also be available contingent upon review by the Internal Advisory Committee. Our mentorship program includes nationally recognized clinical and translational investigators who provide comprehensive training. Their success is evident in the accomplishments of the group of scientists awarded CDP awards over the last 4.5 year. Two of these individuals are now full contributors of this SPORE serving as Co-Leaders of projects. We propose to continue the high standards we have established and evaluate our program annually. We will modify our selection and training processes as required allowing us to continue to train future scientist in translational research on human melanoma throughout the term of this SPORE.