Linking Parent Drug Use and Child Development Across Three Generations

描述（由申请人提供）：这是一份申请，旨在研究父母和祖父母使用药物对儿童和青少年发展的影响和作用机制。我们寻求5年的支持来收集和分析西雅图社会发展项目（SSDP）小组成员的孩子的数据。SSDP （J. David Hawkins， PI）是一项理论驱动的研究，在早期阶段进行预防性干预。代际项目（TIP, Karl G. Hill， PI）研究了SSDP成员的第一个孩子，SSDP G2父母自己，以及他们的伴侣。早期的工作集中在父母吸毒对孩子的影响上。我们建议进行一项后续研究，以扩大数据收集和分析的额外三个波，因为大多数G3儿童过渡到青春期。这将为以下研究提供足够的样本量：1)父母和祖父母以前和现在的药物使用对发育和开始吸毒的影响；2)父母和祖父母以前和现在的药物使用可能影响儿童发育和开始吸毒的机制；3)G2小时候经历的预防性干预对G3的发育环境、G2的养育实践的影响程度；G3的发展结果。这项研究建立在现有的20年纵向研究的基础上，并将与其延伸到30年代平行，没有科学或预算重叠。拟议的研究提供了一个独特的机会来检查三代人之间吸毒的因素，并分析G2在青春期和成年早期吸毒对其养育行为和子女结局的影响。研究结果将促进对父母和祖父母在青春期和成年早期吸毒对儿童发育、行为和吸毒开始的影响的理解，并将为旨在打破药物代际传播循环的预防性干预措施的设计提供具体目标。

DESCRIPTION (provided by applicant): This is an application to examine the effects and mechanisms of action of parental and grandparental drug use on child and adolescent development. We seek 5 years of support to collect and analyze data on the children of the members of the Seattle Social Development Project (SSDP) panel. SSDP (J. David Hawkins, PI) is a theory-driven study with a preventive intervention nested within its early years. The Intergenerational Project (TIP, Karl G. Hill, PI) has studied the firstborn children of SSDP members, the SSDP G2 parents themselves, and their partners. Earlier work focused on effects of parent drug use on children. We propose a follow-up study to extend data collection and analysis for an additional three waves as most G3 children transition into adolescence. This will provide adequate sample sizes for examination of 1) the impact of prior and current parental and grandparental drug use on development and drug use initiation, 2) mechanisms through which prior and current parental and grandparental drug use may affect child development and drug use initiation, and 3) the degree to which benefits from preventive intervention experienced by G2 when they were children affect G3's developmental environment, G2's parenting practices, and G3's developmental outcomes. The study builds on an existing 20-year longitudinal study, and will run parallel to its extension into the 30's, without scientific or budgetary overlap. The proposed study presents a unique opportunity to examine factors linking drug use across three generations and to analyze the effects of G2's drug use during adolescence and early adulthood on their parenting behaviors and on their children's outcomes. Study findings will advance understanding of the effects of parental and grandparental drug use during adolescence and early adulthood on children's development, behavior, and drug use initiation and will provide specific targets for the design of preventive interventions aimed at breaking cycles of intergenerational transmission of drug use. PUBLIC HEALTH RELEVANCE: The study will advance understanding of the effects of parental and grandparental drug use during adolescence and early adulthood on children's development, behavior, and drug use initiation and will provide specific targets for the design of preventive interventions aimed at breaking cycles of intergenerational transmission of drug use.