Biomedical Imaging Informatics Core

生物医学成像信息学核心 生物医学成像信息学核心(BLL)将提供关键的集成成像数据 NIH赞助的国家癌症影像档案馆(NCIA)和癌症生物信息学的网络 GRID(CaBIG)程序。BLL由弗雷德·普赖尔博士执导，工作人员为电子 西科大放射学实验室(ERL)。普赖尔博士和ERL的其他成员一直积极参与 CaBIG的成像工作空间和实验室是可扩展成像平台项目的主承包商 [91][老外谈]。此外，ERL还开发了NCIA的非NCI实例，目前正用于捕获 数字化病理切片图像作为NCI试点项目的一部分。BLL将在很大程度上借鉴这种经验 基地。除了caBIG的参与外，ERL还为国家肺部开发了一个图像库 筛选试验[92]，是3个正在进行的多中心临床试验的成像核心。ERL已经开发出一种 全套软件工具和操作程序，以支持基于成像的临床试验。ERL工作人员 包括普赖尔博士和摩尔先生在内的成员在DICOM医疗标准方面拥有丰富的经验 图像传播，包括作为原始标准(Preor)的联合作者和第一个开放标准的作者 来源，参考实施(摩尔)[93]。 为支持这一NTR应用程序，ERL将建立一个用于捕获和管理所有图像基础设施 由WUSTL网络生成的数据。这项工作的重点将是ERL中的NCIA实例， 将扩展为支持光学和光声图像。ERL还将创建一个或多个目标图像 使用XIP构建器工具分析应用程序。支持光声、光学的新DICOM数据格式 将定义成像和特定的临床前成像类型(小动物成像)，并将其作为 这个项目。ERL还将支持WUSTL网络成员之间的协作和数据共享， 更广泛的正常贸易关系网络。

Biomedical Imaging Informatics Core The Biomedical Imaging Informatics core (Bll) will provide critical integration imaging data generated within the network into the NIH sponsored National Cancer Imaging Archive (NCIA) and the cancer Bioinformatics Grid (caBIG) program. The Bll be directed by Dr. Fred Prior and staffed by members of the Electronic Radiology Laboratory (ERL) at WUSTL. Dr. Prior and other member of ERL have been actively involved in caBIG's imaging workspace and the lab is the prime contractor on the extensible Imaging Platform project [91]. In addition ERL has developed a non-NCI instance of NCIA which is currently being used to capture digitized pathology slide images as part of an NCI pilot project. The Bll will draw heavily on this experience base. In addition to its caBIG involvement ERL has developed an image library for the National Lung Screening Trial [92] and is the imaging core for 3 on-going multi-center clinical trials. ERL has developed a complete suite of software tools and operational procedures to support imaging based clinical trials. ERL staff members including Dr. Prior and Mr. Moore have extensive experience with the DICOM standard for medical image communication, including being a co-author of the original standard (Prior) and author of the first, open source, reference implementation (Moore) [93]. In support of this NTR application, ERL will establish an infrastructure for capturing and managing all image data generated by the WUSTL network. The focal point of this effort will be the NCIA instance in ERL which will be extended to support optical and photoacoustic images. ERL will also create one or more targeted image analysis applications using the XIP builder tool. New DICOM data formats to support photoacoustic, optical imaging and specific pre-clinical image types (small-animal imaging) will be defined and prototyped as part of this project. ERL will also support collaboration and data sharing among members of the WUSTL network and the broader NTR network.