BIOSTATISTICS

总结： 生物统计学核心（指定的共享研究资源核心）将在宾夕法尼亚大学PROSPR研究中心赠款下产生的研究项目的设计，实施和分析的生物统计学方面提供专家指导和支持。核心工作人员将在每个阶段与项目调查人员合作：他们已经协助设计拟议项目，他们将继续与调查人员合作完善设计和分析计划。随着研究的进行。核心工作人员将监测研究数据库，参与数据质量评价，并进行任何指定的中期分析。当研究结束。核心工作人员将进行正确和有效的数据分析，绘制图表，协助调查人员编写介绍和手稿，并就随后的研究设计提供咨询。核心工作人员拥有丰富的经验，支持各种乳腺癌和其他形式癌症的研究项目。特别是，他们在比较有效性研究，癌症诊断，卫生经济学和筛查计划的统计评估方面拥有丰富的专业知识。因此，Core非常有资格为PCIPS提供最高质量的生物统计支持。

Summary: The Biostatistics Core (the designated Shared Research Resources Core) will provide expert guidance and support in the biostatistical aspects of the design, conduct and analysis of research projects generated under the Penn PROSPR Research Center grant. Core staff members will collaborate with project investigators at every stage: They have already assisted in the design of proposed projects, and they will continue to work with investigators in refining design and analysis plans. As studies proceed. Core staff members will monitor study databases, participate in the evaluation of data quality, and conduct any designated interim analyses. When studies are finished. Core staff will conduct correct and efficient data analyses, create graphs and tables, assist investigators with the preparation of presentations and manuscripts, and consult on the design of subsequent research. The Core staff members have extensive experience supporting research projects of all kinds in breast cancer and other forms of cancer. In particular, they have substantial expertise in comparative effectiveness research, cancer diagnostics, health economics, and the statistical evaluation of screening programs. Thus the Core is superbly qualified to provide biostatistical support of the highest quality to PCIPS.