Mentoring and Research in Cancer Palliative Care

描述（申请人提供）：去年，大约有140万美国人被诊断出患有癌症，大约有56万人死于癌症。当人们考虑到与癌症治疗相关的不良事件、临终症状的广泛分布和严重程度以及丧亲之痛的后果时，毫无疑问，癌症引起的痛苦是巨大的，迫切需要对癌症姑息治疗进行研究，以减轻这种痛苦。 博士Jatoi是一名职业生涯中期的研究人员，他正在重新提交一份名为“癌症姑息治疗的指导和研究”的K24申请。“她的职业目标如下：1）在癌症姑息治疗中进行严格的临床和转化研究，短期目标是减轻癌症患者的痛苦; 2）为不同的年轻研究人员提供癌症姑息治疗职业发展的机会，长期目标是再次减轻癌症患者的痛苦。 博士Jatoi非常适合实现这些职业目标。她对癌症姑息治疗进行了多项临床和转化研究，从而产生了120多篇已发表的手稿。这些研究主要集中在缓解癌症相关的厌食症和体重减轻，但有时也集中在其他癌症相关症状的管理上。作为导师和资深作者，Jatoi博士与16名来自不同背景的年轻研究人员一起发表了28篇手稿。最后，马约诊所综合癌症中心坚定不移地致力于患者护理，拥有庞大的临床试验基础设施，全面的实验室资源以及动态的高度协作环境-从而进一步确保该申请的成功。

DESCRIPTION (provided by applicant): Last year, approximately 1,400,000 Americans were diagnosed with cancer, and approximately 560,000 died from it. When one considers the adverse events associated with cancer treatment, the wide constellation and severity of end-of-life symptoms, and the aftermath of bereavement, there is no question that cancer-induced suffering is great and that there is a major need for research in cancer palliative care to relieve this suffering. Dr. Jatoi is a mid-career investigator who is re-submitting a K24 application entitled, "Mentoring and Research in Cancer Palliative Care." Her career goals are as follows: 1) To conduct rigorous, clinical and translational research in cancer palliative care with the short-term goal of relieving suffering among cancer patients; 2) To provide opportunities for career growth in cancer palliative care for a diverse group of young investigators with the long-term goal of, again, relieving suffering among cancer patients. Dr. Jatoi is well suited to meet these career goals. She has conducted multiple clinical and translational studies on cancer palliative care, thus generating over 120 published manuscripts. These studies have focused largely on palliating cancer-associated anorexia and weight loss, but they have also, at times, focused on the management of other cancer-related symptoms. As a mentor and senior author, Dr. Jatoi has published 28 manuscripts with 16 young investigators from highly diverse backgrounds. Finally, the Mayo Clinic Comprehensive Cancer Center holds an unwavering commitment to patient care, a vast clinical trial infrastructure, comprehensive laboratory resources, and a dynamic, highly collaborative environment- thus, further ensuring the success of this application.