CORE C: Statistics & Methodology Services

核心C人员提供出色的统计和方法咨询，他们产生新的知识 通过帮助生物医学和行为研究人员开发解决数据分析问题的最佳方法， 这限制了他们的担忧。“生成性”解决方案与“最新技术水平”不同。“最先进的”是指大多数 专家研究人员所熟知的先进解决方案。“生成式”解决方案超越了最先进的技术水平， 解决方案适时的生成性世界可能会导致在方法学期刊上发表文章。(See核心0出版物 第一节中的出版物列表中有创始人和现任顾问Jennifer Blackiford、Chun Li、Jon Tapp和Lily Wang C3.5.3.5） 随着现代研究复杂性的增加，专业化的统计援助已成为强制性的， 大多数研究人员。当期刊审稿人第一个注意到设计或分析中的问题时， 解决他们。核心0人员帮助研究者开始他们的研究，提供最新的设计和分析计划。 Core C在一个高度协作的环境中运行， 统计和数据库管理方法的应用，并产生新的分析战略， 方法论。核心人员具有观察方法学、生物和行为统计学方面的专业知识， 遗传学、实验设计和多元统计学。核心的专业知识得到了加强， 与范德比尔特大学医学院生物统计学系合作。 自2003年P30核心审查以来，核心0中最重要的变化之一是增加了 与生物医学部合作。VanderiDilt医学院创建了 2003年9月，生物统计学。在这样做的过程中，范德比尔特作出了重大的资金承诺，建立一个世界级的 2010年，该部门将包括一个博士级的博士课程。由Frank E.小哈维尔博士，谁也 作为核心C的主任，这个部门有特殊的机构支持。生物统计学家的愿景 该部门是，他们成为统计科学家谁是生物医学研究的前沿，谁 为医学和生物统计学的知识体系做出贡献。 从历史上看，VKC已经注意到了与人类行为研究相关的统计分析的优势;然而， 2003年，NICHD P30审查小组指出了生物医学统计专业知识的不足。为了满足这一需求， VKC和BioApprofics于2004年建立了合作伙伴关系，包括两名具有生物统计学专业知识的博士生物统计学家。 和Core C中的遗传数据分析（Wang和Li）。2006年任命Frank Han-ell为Core C总监 进一步巩固了伙伴关系。VKC和生物统计部门之间的这种关系一直是 互惠互利该部已扩大其原来的作用以外的医学研究，包括一个大的 一些多学科和转化研究合作，VKC加强了其 行政领导及其向研究者提供高质量生物统计支持的能力。 VKC投资者和受训人员参加Core C提供的研讨会和每日无预约诊所 由生物统计部与包括VKC在内的合作伙伴共同进行。这种富有成效的互动性 这种关系出现在共同撰写的出版物、工作室和培训课程中， VKC调查员的社区。为了说明2003年以来变化的有效性， 2003年至2006年期间，VKC调查员每季度的服务量几乎翻了一番。此外，还有一个平衡的 核心C服务在VKC行为和生物医学研究人员之间的分布。

Core C personnel provide outstanding stafistical and methodological consulting, and they generate new knowledge by helping biomedical and behavioral researchers develop the best approaches to solving data analytic problems that limit their wori<. "Generative" solutions are distinguished from "state of the art." "State of the art" refers to most advanced solutions known to expert researchers. "Generative" solutions push beyond the state of the art with novel solutions. Tmly generative wori^ may lead to published articles in methods journals. (See publications by Core 0 fomner and cun-ent consultants Jennifer Blackiford, Chun Li, Jon Tapp, and Lily Wang in the publication list in Section C3.5.3.5) As the complexity of modem research has inaeased, specialized statistical assistance has become mandatory for most researchers. When joumal reviewers are the first to notice problems in design or analysis, it is often too late to solve them. Core 0 personnel help investigators begin their research with up-to-date designs and analytic plans. Core C operates within a highly collaborative environment that facilitates the use of the most sophisticated application of stafistical and database management methodologies and that generates new analytical strategies and methodologies. Core personnel have expertise in observational methodologies, bio- and behavioral statistics, statisfical genefics, experimental design, and multivariate statistics. The Core's expertise is reinforced by close collaboration with the Department of Biostatistics at the Vanderbilt University School of Medicine. One of the most significant changes instituted in Core 0 since the 2003 P30 review of the Core is increased collaboration with the Department of Biostatisfics. VanderiDilt's School of Medicine created the Department of Biostatistics in September 2003. In doing so, Vanderbilt made a major funding commitment to build a worid-class department that will include a doctoral-level PhD program in 2010. Chaired by Frank E. Harwell, Jr., PhD, who also serves as Director of Core C, this department has excepfional institutional support. The vision for biostatisticians in the Department is that they become statistical scientists who are on the forefront of biomedical research and who contribute to the body of knowledge in medicine and in biostatistics. Historically, the VKC had noted strengths in stafistical analysis related to human behavioral studies; however, in 2003, the NICHD P30 review panel noted shortcomings in biomedical statistical expertise. To address this need, the VKC and Biostatisfics initiated a partnership in 2004 by including two PhD biostatisticians with expertise in biological and genetic data analysis in Core C (Wang and Li). The appointment of Frank Han-ell as Director of Core C In 2006 further cemented the partnership. This relationship between the VKC and the Department of Biostatistics has been mutually beneficial. The Department has extended its original role beyond medical research to include a large number of multidisciplinary and translational research collaborations, and the VKC has strengthened its administrative leadership and its ability to provide high-quality biostatistical support to investigators. VKC invesfigators and trainees participate in workshops offered by Core C and in a daily walk-in clinic implemented by the Department of Biostatistics, with partners that include the VKC. Evidence of this productive, interactive relationship appears in co-authored publications, wori<shops, and training sessions that have been enriching the community of VKC investigators. As an illustration of the effectiveness of the changes since 2003, the number of VKC investigators served each quarter almost doubled between 2003 and 2006. Moreover, there is a balanced distribution of ufilization of Core C services between VKC behavioral and biomedical researchers.