Reducing Obesity in African American Women through Lifestyle Enhancement

迫切需要研究减肥方法，以降低风险和相关的 非裔美国女性肥胖的并发症。根据美国国家健康与营养中心 考试调查(2007-2008)，女性肥胖率(35.5%)高于男性(32.2%) 非西班牙裔黑人的患病率(44.1%)高于非西班牙裔白人(32.8%)，非西班牙裔 黑人妇女报告的患病率最高(49.6%)。肥胖与患糖尿病的风险增加有关 高血压、糖尿病、血脂异常和代谢综合征；糖尿病死亡风险增加， 肾脏疾病，一些癌症，主要是心血管疾病。尽管生活方式因素占了 50%的过早死亡，缺乏循证的临床试验已经打折了生活方式的价值 干预措施是降低高危人群肥胖率的可靠策略。 拟议项目的目标是在非洲-非洲人中进行一项减少肥胖的随机临床试验 美国妇女通过以社区为基础的参与性研究(CBPR)伙伴关系在非洲- 美国教众和调查人员在一个少数族裔、低收入、服务不足的社区。这个 一项拟议的研究将测试一种新的基于生活方式的减肥计划对非洲肥胖人群的影响。 美国妇女在她们的教会中，将高级牧师的直接参与纳入到 计划干预。该项目的具体目标是：1)培养一位促进减肥的教堂牧师 在教堂环境中为肥胖的非裔美国妇女制定的计划，以及，2)评估教堂的影响 帕斯特促进了非裔美国女性的减肥计划，与 一个不是由教堂牧师协助的减肥计划。这项研究的次要目的是测试 减肥对减少心血管疾病风险因素的影响，并测试体重减轻的差异 绝经前和绝经后妇女之间的差异。

There is an urgent need for research on weight loss approaches for reducing the risk and associated complications of obesity in African-American women. According to the National Health and Nutrition Examination Survey (2007 - 2008), women have a higher obesity prevalence (35.5%) than men (32.2%) and non-Hispanic blacks have a higher prevalence (44.1%) than non-Hispanic whites (32.8%), with non-Hispanic black women having the highest prevalence reported (49.6%). Obesity is associated with increased risk of hypertension, diabetes, dyslipidemia, and metabolic syndrome; and increased risk of death from diabetes, kidney disease, some cancers, and primarily cardiovascular diseases. Although lifestyle factors account for 50% of premature mortality, the lack of evidence-based clinical trials has discounted the value of lifestyle interventions as a dependable strategy for reducing obesity prevalence in high-risk populations. The goal ofthe proposed project is to conduct a randomized clinical trial for reducing obesity among African- American women, through a community-based participatory research (CBPR) partnership among African- American congregations and investigators in a high-minority, low-income, underserved community. The proposed study will test the effects of a novel lifestyle-based weight loss program for obese African- American women in their churches, which incorporates the direct participation of Senior Pastors into the program intervention. The project's specific aims are to: 1) develop a church pastor facilitated weight loss program for obese African-American women in the church setting, and, 2) assess the effect of a church pastor facilitated weight loss program for African-American women on decreasing body weight compared to a weight loss program that is not church pastor facilitated. The study's secondary aims are to test the effects of weight loss on reducing risk factors for cardiovascular disease, and to test for differences in weight loss between pre-menopausal and post-menopausal women.