Reducing Obesity in African American Women through Lifestyle Enhancement

迫切需要研究减肥方法，以减少风险和相关风险。 肥胖症的并发症。根据国家健康和营养 根据2007 - 2008年的一项调查，妇女的肥胖患病率（35.5%）高于男子（32.2%）， 非西班牙裔黑人的患病率（44.1%）高于非西班牙裔白人（32.8%）， 据报告，黑人妇女的患病率最高（49.6%）。肥胖与以下风险增加有关： 高血压、糖尿病、血脂异常和代谢综合征;以及糖尿病死亡风险增加， 肾脏疾病，某些癌症，主要是心血管疾病。尽管生活方式因素 50%过早死亡，缺乏循证临床试验使生活方式的价值打了折扣 因此，我们认为，干预措施是降低高危人群肥胖患病率的可靠策略。 该项目的目标是进行一项随机临床试验，以减少非洲人的肥胖， 美国妇女，通过非洲国家和地区之间的社区参与性研究伙伴关系， 美国教会和调查人员在一个高少数民族，低收入，服务不足的社区。的 拟议的研究将测试一种新的基于生活方式的减肥计划对肥胖的非洲人的影响， 美国妇女在她们的教会，其中包括直接参与高级牧师到 方案干预。该项目的具体目标是：1）开发一个教会牧师促进减肥 计划肥胖的非洲裔美国妇女在教会设置，和，2）评估教会的影响， 牧师促进减肥计划，为非洲裔美国妇女减少体重相比， 一个没有教会牧师帮助的减肥计划。这项研究的次要目的是测试 减肥对降低心血管疾病风险因素的作用，并测试减肥 绝经前和绝经后妇女之间的差异。

There is an urgent need for research on weight loss approaches for reducing the risk and associated complications of obesity in African-American women. According to the National Health and Nutrition Examination Survey (2007 - 2008), women have a higher obesity prevalence (35.5%) than men (32.2%) and non-Hispanic blacks have a higher prevalence (44.1%) than non-Hispanic whites (32.8%), with non-Hispanic black women having the highest prevalence reported (49.6%). Obesity is associated with increased risk of hypertension, diabetes, dyslipidemia, and metabolic syndrome; and increased risk of death from diabetes, kidney disease, some cancers, and primarily cardiovascular diseases. Although lifestyle factors account for 50% of premature mortality, the lack of evidence-based clinical trials has discounted the value of lifestyle interventions as a dependable strategy for reducing obesity prevalence in high-risk populations. The goal ofthe proposed project is to conduct a randomized clinical trial for reducing obesity among African- American women, through a community-based participatory research (CBPR) partnership among African- American congregations and investigators in a high-minority, low-income, underserved community. The proposed study will test the effects of a novel lifestyle-based weight loss program for obese African- American women in their churches, which incorporates the direct participation of Senior Pastors into the program intervention. The project's specific aims are to: 1) develop a church pastor facilitated weight loss program for obese African-American women in the church setting, and, 2) assess the effect of a church pastor facilitated weight loss program for African-American women on decreasing body weight compared to a weight loss program that is not church pastor facilitated. The study's secondary aims are to test the effects of weight loss on reducing risk factors for cardiovascular disease, and to test for differences in weight loss between pre-menopausal and post-menopausal women.