Medical Imaging Motion Monitor (MIMM)

描述（由申请人提供）：由于需要大量时间来获取足够的计数以生成临床质量图像，因此患者运动是核医学成像研究中的一个主要问题。存在运动校正算法，但其准确性和有效性有限，并且在许多情况下，唯一实际的替代方案是重新扫描患者。关于患者运动感测的大多数工作都集中在光学跟踪系统上。虽然在研究实验室中已经达到亚毫米精度，但是外部光学跟踪系统的成本、复杂性和视线要求阻止了它们在临床核医学部门的常规使用。对于用于核医学研究的实用且廉价的患者运动感测设备存在未满足的临床需求。这对于需要高分辨率和精确定量的脑PET和SPECT研究尤其如此，这两者都可能因患者运动而严重退化。我们提出了一种新颖的和廉价的方法，头部跟踪脑PET和SPECT研究，满足这些实际要求。我们在第一阶段的目标是开发必要的硬件和软件，准确的头部运动传感，并验证这种方法在临床脑PET和SPECT研究。

DESCRIPTION (provided by applicant): Patient motion is a major issue in nuclear medicine imaging studies due to the substantial time to acquire enough counts to produce clinical-quality images. Motion correction algorithms exist but have limited accuracy and effectiveness, and in many instances the only practical alternative is to re-scan the patient. Most work on patient motion sensing has focused on optical tracking systems. Although sub-millimeter accuracy has been attained in research laboratories, the cost, complexity, and line-of-sight requirement of external optical tracking systems have prevented their routine use in clinical nuclear medicine departments. There is an unmet clinical need for a practical and inexpensive patient motion sensing device for nuclear medicine studies. This is especially true for brain PET and SPECT studies which demand high resolution and accurate quantification, both of which may be severely degraded by patient motion. We propose a novel and inexpensive method for head tracking for brain PET and SPECT studies that satisfies these practical requirements. Our aims in phase I are to develop the necessary hardware and software for accurate head motion sensing and to validate this method in clinical brain PET and SPECT studies.