Addition of Pediatric TBI Data to FITBIR

描述(申请人提供)：儿童受伤后健康(CHAI)研究由美国疾病控制与预防中心资助(2006年9月至2012年8月)，以确定儿童和青少年创伤性脑损伤(TBI)后基于人群的伤残率。这项研究是关于儿童脑损伤的最大的前瞻性纵向研究之一，有超过三年的出色随访，包括对照，提供了对脑损伤后功能结果的全面检查，并收集了大量干净和有效的数据。这些高质量的数据目前可以输入联邦机构间创伤性脑损伤研究(FITBIR)数据库，并与其他现有或未来的儿科数据结合起来，推动儿科脑损伤研究领域的发展。仍有许多问题可以结合这些遗留数据和其他儿科TBI数据输入FITBIR进行探索。具体地说，遗留的CHAI数据将可用于研究：1.中、重度脑损伤后治疗对1、2和3年结果的影响2.脑损伤及其治疗对学习结果的影响3.儿童脑损伤后青少年报告的功能结果与父母报告的结果比较4.儿童脑损伤后的结果比较5.不同年龄段儿童和成人脑外伤后预后的比较本建议的具体目的是：1.将CHAI数据映射到FTBIR中的公共数据元素(CDE)中。提供不在CDE中但可能对未来的儿科脑损伤研究有帮助的额外的儿科脑损伤数据3.将重新格式化的CHAI数据传送到FITBIR中

DESCRIPTION (provided by applicant): The Child Health After Injury (CHAI) study was funded by the CDC (9/2006 to 8/2012) to determine the population-based rates of disability after traumatic brain injury (TBI) to children and adolescents. This study was one of the largest prospective longitudinal studies on pediatric TBI, had outstanding follow-up over three years, included controls, provided a comprehensive examination of functional outcomes after TBI and collected a wealth of clean and validated data. These high quality data are currently available to be entered into the Federal Interagency Traumatic Brain Injury Research (FITBIR) database and combined with other existing or future pediatric data to advance the field of pediatric TBI research. There are still a number of questions which could be explored using these legacy data in combination with other pediatric TBI data to be entered into FITBIR. Specifically, the legacy CHAI data would be available for use to study: 1. Effects of treatment on 1, 2 and 3 year outcomes after moderate or severe TBI 2. Effects of TBI and its treatment on school outcomes 3. Comparison of adolescent reported functional outcomes after pediatric TBI to parent reported outcomes 4. Comparison of outcomes after TBI in children < 5 years due to abuse with that due to unintentional mechanisms 5. Comparison of outcomes after TBI in children at different ages as well as to adults The specific aims of this proposal are to 1. Map the CHAI data into the common data elements (CDE) in FTBIR 2. Provide additional pediatric TBI data not in CDE but which may be helpful to future pediatric TBI studies 3. Deliver the reformatted CHAI data into FITBIR