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中文摘要
翻译
美国国家癌症研究所(NCI)的流行病学和基因组学研究计划(EGRP),在癌症控制和人口科学部(DCCPS)的使命是资助在人群中的研究,以了解癌症的原因和相关结果。该方案促进跨学科合作以及资源和技术的开发和利用,以推进癌症研究及其转化,作为临床和公共卫生干预的基础。肿瘤遗传关联机制(GAME-ON)是gwas后癌症倡议,是EGRP资助的研究的一个很好的例子。
英文摘要
The mission of the National Cancer Institute’s (NCI) Epidemiology and Genomics Research Program (EGRP), in the Division of Cancer Control and Population Science (DCCPS), is to fund research in human populations in order to understand the causes of cancer and related outcomes. The Program fosters interdisciplinary collaborations and the development and use of resources and technologies to advance cancer research and its translation to serve as the basis for clinical and public health interventions. The Genetic Association mechanisms in Oncology (GAME-ON), a Cancer Post-GWAS Initiative, is a great example of the research funded by EGRP. GAME-ON consists of five multidisciplinary teams of epidemiologists, basic scientists, and clinicians who are collaborating to investigate genomic regions that have been implicated in susceptibility to breast, colon, ovarian, prostate, and lung cancer. GAME-ON will rapidly move forward promising leads from initial cancer GWAS by replicating prior findings, better pinpointing genomic regions involved in cancer susceptibility, and unraveling the functional consequences of genetic variants and how environmental factors may influence the genetic effect, in order to set the stage for translating these findings into clinical and prevention applications. The mandated in-person meetings are essential for a number of reasons, such as establishment of internal structures and policies, discussion and planning of collaborative projects and early reporting of yet unpublished research results.
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CONFERENCE & MEETING SUPPORT SERV. F/THE DNBBS, NIMH
  • 批准号:
    7542405
  • 项目类别:
  • 资助金额:
    $4.3万
  • 财政年份:
    2005
  • 负责人:
    MATT BURDETSKY
  • 依托单位:
    --
NHP Reagent Resource for immune-mediated diseases, tranplantation, and infectious
Task 03 (F02): NDA Enabling Nonclinical Studies for Evaluation of ST-246
  • 批准号:
    8332207
  • 项目类别:
  • 资助金额:
    $0.22万
  • 财政年份:
    2004
  • 负责人:
    MATT BURDETSKY
  • 依托单位:
Vaccine and Treatment Evaluation Units (VTEUs)
  • 批准号:
    8351909
  • 项目类别:
  • 资助金额:
    $15.45万
  • 财政年份:
    2002
  • 负责人:
    MATT BURDETSKY
  • 依托单位:
海外基金