NCI CBIIT PROGRAM MANAGEMENT SUPPORT

由美国国家癌症研究所(NCI)开发的癌症生物医学信息网格(CABIG(R))有助于克服在21世纪实现个性化医疗的几个关键障碍。CaBIG(R)通过多学科的合作研究，帮助利用大量的基因组和临床数据，更快、更有可能以更低的成本将新的诊断和治疗方法应用于癌症和其他疾病，最终改善患者的结果。通过实施语义和句法上可互操作的信息技术(IT)基础设施，将NCI指定的60多个综合癌症中心彼此连接起来，并连接到更广泛的生物医学界，caBIG(R)已经对美国的癌症研究产生了革命性的影响。CaBIG(R)计划不仅仅是一个软件工具的技术堆栈，更重要的是，它是一个由不同利益相关者组成的丰富社区，其中包括研究人员、临床医生、管理人员、患者权益倡导者以及来自政府、学术界和工业界的其他利益相关者。虽然NCI设计这一计划的目的是为了加速发现，从而更好地检测、治疗和预防癌症，但它也被设计为扩展到支持其他医疗条件下的相同努力。为此，NCI发起了一个名为BIG Health的姊妹计划，目的是促进caBIG(R)技术在癌症以外的应用。

The cancer Biomedical Informatics Grid(R) (caBIG(R)) developed by the National Cancer Institute (NCI), helps overcome several critical obstacles to enabling personalized medicine in the 21st century. caBIG(R) helps leverage large quantities of genomic and clinical data through multidisciplinary, collaborative research to bring new diagnostics and therapeutics to bear on cancer and other diseases, more quickly and potentially at reduced cost, ultimately leading to improved patient outcomes. By implementing a semantically and syntactically interoperable information technology (IT) infrastructure to connect the 60+ NCI-designated Comprehensive Cancer Centers to one another and to the broader biomedical community, caBIG(R) is already having a transformative impact on cancer research in the United States. The caBIG(R) program is not just a technology stack of software tools but more importantly is a rich community of diverse stakeholders including researchers, clinicians, administrators, patient advocates, and other stakeholders from Government, academia, and industry. Though the NCI designed this program for the purpose of accelerating discovery toward better detection, treatment, and prevention of cancer, it was also designed to be extended to support the same endeavor for other medical conditions. To that end, the NCI has launched a sister initiative called BIG Health, with a purpose to facilitate utilization of caBIG(R) technology beyond cancer.