Duke Training Grant in Nephrology

描述（由申请人提供）：肾脏病学培训补助金肾脏病学杜克培训补助金的目的是为博士后研究员提供集中的研究培训，重点是与正常肾脏生理学，肾脏疾病和高血压的发病机制有关的领域。该计划的主要目标是培养具有肾脏病学和高血压研究专业知识的学术医生以及基础，翻译和临床科学家。该计划提供了基础和临床研究培训的各种机会，从而使学员能够发展必要的技能和灵活性， 肾脏病学的研究需求。我们的教师在一系列学科中拥有广泛的兴趣和专业知识，提供生理学，分子和细胞生物学，生物化学以及与转基因小鼠相关的技术的综合培训。对于对临床研究感兴趣的学员，正在进行的生物统计学，决策分析，人类遗传学和代谢组学课程为严格评估与高血压和肾脏疾病相关的临床问题提供了基础。我们认为，获得成为一名成功的医生科学家所需的研究技能，最好是通过与质量导师密切合作的两到三年的密集实验室经验来完成。因此，研究计划的结构是在导师的监督下最大限度地利用实验室时间。对于具有医学博士学位的学员学位，该计划旨在提供一年的临床培训，随后至少两年的研究培训，将由本申请中要求的资金支付。正式的课程工作，研究研讨会和期刊俱乐部补充了这一实验室的经验。我们预计，参加该计划的学员的经验水平将包括最低研究经验的研究员，以及高级研究培训的研究员，包括博士研究员。度我们正在申请资金，以支持每年三个博士后职位的研究员谁将进行至少两年的并行研究培训。该计划的完成应允许学员追求学术医学的职业生涯与技能进行高质量的研究，在肾脏病学的临床，转化和基础方面。

DESCRIPTION (provided by applicant): Nephrology Training Grant The purpose of the Duke Training Grant in Nephrology is to provide intensive research training for postdoctoral fellows focusing on areas that relate to normal kidney physiology, the pathogenesis of kidney diseases and hypertension. The primary goal of the program is to produce academic physicians as well as basic, translational and clinical scientists with investigative expertise in nephrology and hypertension. The program provides diverse opportunities for training in both basic and clinical research which in turn, permits trainees to develop the skills and flexibility necessary to respond to research demands in nephrology over the coming years. Our faculty have a wide range of interests and expertise in an array of disciplines providing integrated training in physiology, molecular and cellular biology, biochemistry, and technologies relating to genetically modified mice. For trainees interested in clinical research, ongoing programs in biometrics, decision analysis, human genetics and metabolomics provide a basis for rigorous evaluation of clinical issues related to hypertension and diseases of the kidney. We believe that the acquisition of research skills required to become a successful physician scientist is best accomplished by two to three years of intensive laboratory experience working closely with a quality preceptor. The research program is, therefore, structured to maximize time in the laboratory under the supervision of a mentor. For trainees with M.D. degrees, the program is designed to provide one year of clinical training followed by at least two years of research training that will be supporte by funds requested in this application. Formal course work, research seminars, and journal clubs supplement this laboratory experience. We anticipate that the levels of experience for trainees participating in the program will encompass fellows with minimal research experience to fellows with advanced research training including fellows with Ph.D. degrees. We are requesting funds to support three postdoctoral positions per year for fellows who will undertake at least two years of concurrent research training. Completion of this program should allow trainees to pursue careers in academic medicine with the skills to conduct high-quality research in clinical, translational and basic aspects of nephrology.