Health Promotion and Disease Prevention Research Center

 描述(申请人提供)：阿尔茨海默病及相关疾病(AD)影响560万美国人，不分种族、民族或文化背景，这是一个重大的公共卫生挑战，只会随着美国人口老龄化而增加。美国人口普查局估计，到2050年，超过五分之一的美国人口将达到65岁及以上。85岁及以上的最脆弱群体将经历最大的增长率。2000年，这些人口占美国人口的1.5%；到2050年，他们将占到近5%。据估计，每个痴呆症患者都有2.9名家庭照顾者。很少有人注意到文化信仰和社会人口因素(年龄、性别、教育、语言、种族、民族)对患者和家属对AD的症状、症状、病因、治疗或管理、他们的疾病经历或这些因素如何影响健康结果的理解的作用和影响。在高加索人群中已经进行了大量的AD护理研究；据估计，到2050年，老年美国人中非裔美国人、西班牙裔美国人或亚裔美国人的比例将增加到39%。为了有效地应对AD流行，我们致力于以下目标：(A)制定关于认知健康和认知障碍的循证公共卫生信息，以引起不同的老年人及其家庭、他们的医疗保健提供者和政策制定者的共鸣；(B)确定传播这些信息的最有效方式；以及(C)将这些信息转化为健康促进和预防计划，以促进降低风险，促进早期发现、诊断和治疗，并增加对AD临床研究的参与。为了实现我们的目标，我们建议开展以下活动：1)进行范围界定审查，并创建促进者和障碍简编；2)对来自不同背景的4个AD患者焦点小组和4个与其家庭照顾者的焦点小组的结果进行和分析；3)召集利益相关者咨询联盟，提供专家指导和见解；4)利用城市和州范围的联系，将结果和概要传播到公共卫生和临床研究网络；以及5)评估传播和社区翻译方法的有效性。这一应用有可能对改善公共卫生实践的循证信息产生持续影响。此外，我们的跨文化方法可以推广到更广泛的实施中。

 DESCRIPTION (provided by applicant): Alzheimer's disease and related disorders (AD) affects 5.6 million Americans regardless of racial, ethnic or cultural background, presenting a significant public health challenge that will only increase with aging of the US population. By 2050, the US Census Bureau estimates that over one-fifth of the US population will be 65 and older. The greatest rate of increase will be experienced in the most vulnerable group those 85 and older. In 2000, this population represented 1.5% of the US population; by 2050, they will comprise almost 5%. Each, with each person with dementia is estimated to have 2.9 family caregivers. Little attention has been placed on the role and impact of cultural beliefs and sociodemographic factors (age, gender, education, language, race, ethnicity) on the patient's and families' understanding of the signs, symptoms, causes, treatment or management of AD, their disease experiences, or how these factors influence health outcomes. Much AD caregiving research has been done in Caucasian populations; by 2050 it is estimated that the proportion of elder Americans who are African American, Hispanic, or Asian American will increase to 39%. To effectively attend to the AD epidemic we address SIP-14-003 with the following OBJECTIVES: (a) develop evidence- based public health messages about cognitive health and impairment that resonate with diverse populations of older adults and their families, their health care providers, and policy makers; (b) determine the most effective ways to disseminate these messages; and (c) translate these messages into health promotion and prevention programs that promote risk reduction, facilitate early detection, diagnosis and treatment, and increase participation in AD clinical research. To achieve our objectives, we propose the following activities: 1) Perform a scoping review and create a compendium of facilitators and barriers; 2) Conduct and analyze results from 4 focus groups of AD patients from diverse backgrounds and 4 focus groups with their family caregiver; 3) Convene a Stakeholder Advisory Coalition to provide expert guidance and insight; 4) Leverage city- and state- wide connections and disseminate the findings and the compendium to the public health and clinical research networks; and 5) Evaluate effectiveness of dissemination and community translation approaches. This application has the potential to have sustained influence on the evidence-based messages for improved public health practice. Furthermore, our cross-cultural approach can be generalized for broader implementation.