NYU Collaborative Center In Children's Environmental Health Research and Translation

纽约大学儿童环境健康研究与翻译合作中心

• 批准号: 10542341
• 负责人: CHAU TRINH-SHEVRIN
• 金额: $ 84.75万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-12-17 至 2026-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10542341
• 关键词: Adoption; Asian Americans; Behavior; Behavior Therapy; Biological Markers; Chemicals; Child; Child Health; Clinical Sciences; Communities; Community Health; Development; Diet; Disease; Energy consumption; Environment; Environmental Hazards; Environmental Health; Evidence based intervention; Expenditure; Exposure to; Flame Retardants; Funding; Guidelines; Health; Home; Hospitals; Household; Human; Infrastructure; Intervention; Investigation; Knowledge; Laboratories; Low income; Mentors; Methods; Minority; Modeling; Modification; Multiple Birth Offspring; Muslim religion; National Institute of Environmental Health Sciences; National Institute on Minority Health and Health Disparities; Organophosphates; Outcome; Pesticides; Pilot Projects; Policies; Poly-fluoroalkyl substances; Population; Population Heterogeneity; Prevention Research; Prevention strategy; Procedures; Public Health; Public Health Practice; Research; Research Personnel; Resources; System; Testing; Time; Training; Translational Research; Translations; Work; bisphenol A; built environment; cohort; design; dietary; disability; disorder prevention; dissemination research; economic evaluation; evidence base; exposure reduction interventions; hazard; health communication; health economics; health equity; implementation science; improved; innovation; low health literacy; manufacture; obesity in children; obesogenic; phthalates; polybrominated diphenyl ether; repository; success; therapy design; tool; uptake

PROJECT SUMMARY (OVERALL) The NIEHS/EPA Children's Environmental Health (CEH) and Disease Prevention Centers have rapidly unraveled the contribution of chemical hazards to disease and disability. Substantial progress has been made to develop interventions that reduce exposure, yet uptake and adoption of interventions remains limited at the community and systems levels, in public health practice, and nationally. Most interventions have not been adapted for diverse populations or settings, nor are they typically designed to scale, especially for low-income, minority and low health literacy populations with disproportionate exposure. And few studies have rigorously quantified the impacts of manufacturing changes, policy interventions, or dietary and other behavioral interventions designed to reduce exposure. To achieve higher population-wide impact, CEH researchers require expertise on dissemination research, implementation science methods and public health practice frameworks to cross the translational bridge and achieve success in scaling evidence-based interventions across communities for maximum impact. The objective of our proposed NYU Collaborative Center in Children's Environmental Health Research and Translation (CEHRT) is to serve as a Resource for the CEH community by: (1) developing meaningful prevention and intervention strategies that have promise to scale, (2) adapting these strategies for diverse populations or settings, to achieve higher population-wide impact, and (3) rigorously quantifying the impacts of manufacturing changes, policy interventions, or dietary and other behavioral interventions designed to reduce exposure. NYU CEHRT unites the expertise of four existing translational Centers to meet these urgent challenges and protect children from environmental hazards. The cross-cutting themes of NYU CEHRT include: intervention testing, implementation science, health equity and economic evaluation. NYU CEHRT is also home to two Environmental Influences on Child Health Outcomes (ECHO) cohort centers (UH3OD023305 and UH3OD023332), and therefore extremely well-poised to integrate new knowledge about emerging exposures likely to emerge from ECHO and the broader CEH community. It leverages the expertise of a world-class analytical chemist, Kurunthachalam Kannan, whose NIEHS Human Health Exposure Analysis Resource laboratory (U2CES026452) can support and stimulate innovative pilot projects to rigorously examine changes in biomarkers of exposure resulting from modifications in diet, behavior and household factors. NYU CEHRT will create a robust, mentored training environment that stimulates and supports innovation by early stage investigators in promising time-sensitive, applied or interventional CEH research. It will advance translational CEH research through innovative pilot projects to test and adapt promising or evidence-based interventions in diverse settings, and utilize implementation science and dissemination research frameworks to improve uptake and adoption of CEH research findings.

项目总结（总体）