Basic Immunology Training Program

描述（由申请人提供）：杜克大学免疫学研究生课程建议继续其基础免疫学培训计划。培训计划的主要目标是选择有才华的博士前候选人，并通过正式课程，研讨会和独立研究为他们在基础免疫学领域的杰出和富有成效的研究事业做好准备。培训教师由23名免疫学家组成，他们在免疫学系担任初级或二级职位。本系为受训者提供了在一系列当代免疫学研究领域进行严格培训的机会，例如：淋巴细胞发育和功能机制，包括谱系测定、V(D)J重组、类开关重组、体细胞超突变、细胞信号传导、效应细胞分化、淋巴细胞稳态、免疫记忆和免疫耐受；先天免疫和炎症的机制，包括巨噬细胞、树突状细胞、肥大细胞和补体功能；宿主对细菌、病毒和真菌病原体的防御机制自身免疫;抗肿瘤免疫;还有疫苗开发。寻求资金支持每年培养四名博士预科生。一个遴选委员会将在免疫学研究生课程中选出最优秀的二年级和三年级博士预科生，以获得培训计划的支持。将特别强调征聘和选拔优秀的代表性不足的少数民族受训人员。精心设计的核心课程将为学员提供基础免疫学，生物化学，细胞生物学，分子生物学和遗传学的精湛基础。受训者将接受研究伦理方面的正式培训，以确保他们以最高的学术诚信标准进行研究。受训人员亦会

DESCRIPTION (provided by applicant): The Duke University Graduate Program in Immunology proposes a continuation of its Basic Immunology Training Program. The main objective of the Training Program is to select talented predoctoral candidates and to prepare them, through formal coursework, seminars and independent research, for outstanding and productive research careers in basic immunology. The training faculty consists of 23 immunologists who hold primary or secondary appointments in the Department of Immunology. This faculty provides trainees with opportunities for rigorous training in a range of areas of contemporary immunologic research, for example: mechanisms of lymphocyte development and function, including lineage determination, V(D)J recombination, class switch recombination, somatic hypermutation, cell signaling, effector cell differentiation, lymphocyte homeostasis, immunological memory and immunological tolerance; mechanisms of innate immunity and inflammation, including macrophage, dendritic cell, mast cell and complement function; mechanisms of host defense against bacterial, viral and fungal pathogens; autoimmunity; anti-tumor immunity; and vaccine development. Funds are sought to support the training of four predoctoral students per year. A selections committee will choose the most outstanding second and third year predoctoral trainees in the Graduate Program in Immunology for support by the Training Program. Special emphasis will be placed on the recruitment and selection of outstanding underrepresented minority trainees. A carefully crafted core curriculum will provide trainees with superb grounding in basic immunology, biochemistry, cell biology, molecular biology and genetics. Trainees will receive formal training in research ethics to insure that they will conduct their research with the highest standards of academic integrity. Trainees will also be provided a range of career development opportunities so that they are best equipped to parlay their training into productive and rewarding career paths.