Border Biomedical Research Center

描述（申请人提供）：边境生物医学研究中心（BBRC）。德克萨斯大学埃尔帕索分校（UTEP）与地区学术、政府和私人团体合作，目标是维持和发展现有的BBRC基础设施和项目，以便对美墨边境普遍存在的健康差异进行高质量的研究。这一目标将通过实现四个具体目标来实现。这些目标是：(1)重点加强三个研究领域的优势，以更好地了解原因和机制。这些“群集”是(a)传染病和免疫，(b)由环境毒物引起的癌症和疾病，以及(c)不同的神经调节障碍。追求将更加强调流行病学以及与临床和公共卫生专家的合作。(2)加强研究基础设施，通过(a)加强分子和细胞生物学研究以及生物统计学和生物信息学咨询的多用户核心设施，(b)创建一个新的倡议，即社区参与核心，(c)招聘新的教职员工研究边境卫生问题，(d)专业培养BBRC调查员，从而提高越来越多的调查人员的能力；(e)实施一项强调跨学科研究的试点资助计划，以及(f)建立一个全学院范围的研讨会和两年一次的国际研讨会，通过实践强调BBRC高度重视社区参与、网络、合作和转化研究。加强基础设施包括支持研究的实体工厂组成部分，协调、管理和管理方案组成部分的行政核心部分，以及评估实现方案和边境卫生目标进展情况的评价组成部分。(3)通过在包括教学在内的各种BBRC活动中更加强调基础科学与应用科学之间的相互作用以及实验室发现中实用性的重要性，来强调BBRC研究的转化。(4)通过BBRC的集体活动，创造一个具有全国竞争力的研究环境，以支持生物科学博士项目，作为培养未来研究人员和扩大研究人力的一种手段。

DESCRIPTION (provided by applicant): Border Biomedical Research Center (BBRC). The University of Texas at El Paso (UTEP), in collaboration with regional academic, governmental and private groups, has as a goal, to sustain and grow extant BBRC infrastructure and programs to enable high quality research on health disparities prevalent on the U.S. Mexico border. This goal will be obtained through achievement of four specific objectives. These are to: (1) Focus on augmenting three research areas of strength to better understand causes and mechanisms. These "clusters" are (a) infectious diseases and immunity, (b) cancer and diseases caused by environmental toxicants, and (c) distinct neuro-modulation disorders. Pursuits will be with greater emphasis on epidemiology and collaborations with clinical and public health specialists. (2) Strengthen research infrastructure to enhance capabilities of growing numbers of investigators through (a) enhancement of multi-user core facilities for research in molecular and cell biology and consultation in biostatistics and bioinformatics, (b) creation of a new initiative, the Community Engagement Core, (c) recruitment of new faculty members to research border health issues, (d) development, professionally, of BBRC investigators, (e) implementation of a pilot grant program emphasizing inter-disciplinary research, and (f) establishment of an institution-wide seminar and a biennial international symposium that underscore through practice BBRC's heightened emphasis on community engagement, networking, collaboration and translational research. Included in infrastructure enhancement are physical plant components that support research, an administrative core to coordinate, manage and govern program components, and an evaluative component to assess progress in achieving program- and border health objectives. (3) Accentuate translation of BBRC research through greater emphasis in various BBRC activities, including teaching, of the interplay between basic and applied science and the importance of utility in laboratory discoveries. (4) Create, through collective BBRC activities, a nationally competitive research environment to support the doctoral program in Biological Sciences as a means to develop future researchers and amplify investigative manpower.