IGF::OT::IGF: Expert Meeting on Assessing and Encouraging Interaction between Gen

NIA寻求由人口委员会（CPOP）和行为，认知和感官科学委员会（BBCSS）组织的小型专家组的意见，以了解遗传学如何为社会和行为模型提供信息，以促进该领域的跨学科研究。最近在老龄化的大型纵向研究中的可用性（例如，健康与退休研究、英国老龄化纵向研究和威斯康星州纵向研究）为研究人员提供了探索行为和社会表型的遗传基础的机会，这些表型似乎可以解释健康和疾病的差异。例如，较高的教育程度与许多重要的积极健康和福祉结果有关，包括对阿尔茨海默病的相对保护。最近，一个大型协会已经提出了证据，表明特定的基因变异确实解释了教育程度的一小部分变异性（Rietveld等人，2013年科学），但我们如何将这一点和其他预期的未来发现纳入行为和社会模型尚不清楚。这项NAS活动将帮助NIA促进遗传学和行为/社会科学之间的新研究和合作。

NIA seek input from a small expert group, organized by Committee on Population (CPOP) and the Board on Behavioral, Cognitive, and Sensory Sciences (BBCSS) on how genetics can inform social and behavioral models in order to foster interdisciplinary research in this area. The recent availability in large longitudinal studies of aging (e.g., the Health and Retirement Study, the English Longitudinal Study of Ageing, and the Wisconsin Longitudinal Study) has afforded the opportunity for researchers to explore the genetic underpinnings of behavioral and social phenotypes that appear to explain differences in health and disease. Higher educational attainment, for example is linked to many important positive health and well-being outcomes, including relative protection from Alzheimer¿s disease. Recently, one large consortium has presented evidence that specific gene variants do explain a small fraction of the variability in educational attainment (Rietveld et al., 2013 Science), but how we will incorporate this and other expected future findings into behavioral and social models is unclear. This NAS activity will help NIA foster new research and collaborations between genetics and behavioral/social science.