NIA IRP Comparative Medicine Section
NIA IRP Comparative Medicine Section
批准号:
8736979
负责人:
Luigi Ferrucci
金额:
$411.99万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AccreditationAnimal Care and Use CommitteesAnimal ExperimentationAnimal HousingAnimal WelfareAnimalsAreaBehavioral ResearchBiomedical ResearchCaringChairpersonEducational process of instructingEnsureFutureGeneticGuidelinesHousingInternationalLaboratory AnimalsMedicineMissionMusPersonal SatisfactionProceduresRegulationResearchResearch PersonnelResearch SupportResourcesScientistSiteTestingTrainingUnited States National Institutes of HealthUpdateWorkanimal carecomparativemeetingsprograms
中文摘要
CMS支持NIA科学家的研究。这种支持的一个关键重点是对研究动物进行人道关怀和处理方面的培训。CMS负责研究动物的住房和照料,并确保它们的福祉。NIA动物保护和使用委员会(ACUC)每年至少两次检查和评估动物项目和动物实验室区域,以符合联邦法规和指导方针。CMS致力于建立稳固和一致的资源管理,同时加强与调查人员的合作关系。这些努力对于确保最佳利用现有资源,同时满足调查人员的需要至关重要。
通过NIA CMS提供的培训确保所有动物处理符合NIA、NIH以及联邦法规和指南,以继续保证国际实验动物护理评估和认可协会(AAALACi)的全面认证。NIA CMS还开发和/或建议改进人文关怀和处理,并为NIA内部研究人员提供培训。
所有使用动物的NIA研究人员都必须完成针对设施的培训。该培训包括进入设施的要求、正确的动物处理程序以及其他相关问题。NIA APD和ACUC主席还在NIA每月会议上提供新的/修订的联邦、NIH和/或NIA动物福利指南的更新。
BRC动物收容区进行了翻新,GRC中所有饲养的动物都被搬进了翻新的空间。GRC工厂被废弃了。
每三年,NIA动物计划都会由认证组织AAALACi进行评估。AAALACi网站游客在2013年7月参观了BRC。NIA动物项目的认证状态正在等待AAALAC理事会关于认证的决定,但完全持续的认证是预期的。
CMS继续冷冻保存重要的小鼠品系。今年,20个小鼠品系被超低温保存,将动物从该计划中移除,同时保留它们独特的基因以备将来使用。
英文摘要
The CMS supports the research of NIA scientists. A critical focus of this support is training in the humane care and handling of research animals. CMS is responsible for housing and care of research animals and for ensuring their well-being. The animal program and animal laboratory areas are inspected and evaluated at least twice each year by the NIA Animal Care and Use Committee (ACUC), in compliance with federal regulations and guidelines. CMS works to establish firm and consistent resource management while enhancing a collaborative relationship with investigators. These efforts are critical to insure the optimal use of available resources while meeting the needs of the investigators.
The training offered through NIA CMS ensures that all animal handling is in compliance with NIA, NIH, and federal regulations and guidelines for the continued assurance of full accreditation by the Association for the Assessment and Accreditation of Laboratory Animal Care, International (AAALACi). The NIA CMS also develops and/or recommends refinements in humane care and handling and provides training to NIA intramural researchers.
All NIA research staff using animals are required to complete facility-specific training. This training includes requirements for facility entry, proper animal handling procedures, and other related issues. The NIA APD and ACUC Chairperson also provide updates on new/revised Federal, NIH, and/or NIA animal welfare guidelines at monthly NIA meetings.
The BRC animal holding area was renovated and all animals housed in the GRC were moved into the renovated space. The GRC facility was abandoned.
Every three years the NIA animal program is assessed by the accrediting organization AAALACi. AAALACi site visitors toured the BRC in July 2013. The NIA animal program accreditation status is awaiting the decision of the AAALAC Council on Accreditation but full continuing accreditation is expected.
CMS continues to cryopreserve important mouse lines. Twenty mouse lines were cryopreserved this year, removing animals from the program while conserving their unique genetics for future use.
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科研奖励(0)
会议论文
THE INCHIANTI FOLLOW-UP STUDY-260012111
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批准号:6828820
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
Temporary CARD Facility
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批准号:10291099
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项目类别:
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资助金额:$3029.09万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
NIGMS CCMF allocation
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批准号:8744620
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项目类别:
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资助金额:$15.43万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
The BLSA Home Visit Program
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批准号:8552540
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项目类别:
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资助金额:$9.83万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
The Energetic Pathway to Disability in Older Persons
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批准号:8736674
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项目类别:
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资助金额:$26.46万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
Characterization Of TGF-b Signaling In a B-cell Lymphoma Cell Line
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批准号:8335774
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项目类别:
-
资助金额:$30.19万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
The VALIDATE study
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批准号:8335795
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项目类别:
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资助金额:$10.68万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
NIA IRP Comparative Medicine Section
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批准号:9550723
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项目类别:
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资助金额:$726.68万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
NIBIB CCMF allocation
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批准号:8933904
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项目类别:
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资助金额:$160.98万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
NINDS CCMF allocation
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批准号:8557136
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项目类别:
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资助金额:$2204.6万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
Structure-function relationship of NFkB p65
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批准号:8335862
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项目类别:
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资助金额:$23.22万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
Genetic Analysis Of Klotho In Diseases Of Aging
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批准号:8335889
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项目类别:
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资助金额:$8.36万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
The Aging Genome Association Study "AGE-GAIN"
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批准号:8335996
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项目类别:
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资助金额:$27.4万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
The InChianti Study
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批准号:9565909
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项目类别:
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资助金额:$16.36万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
The InChianti Study
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批准号:10012639
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项目类别:
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资助金额:$8.2万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
Microbiome Projects in the Baltimore Longitudinal Study of Aging
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批准号:10012638
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项目类别:
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资助金额:$8.2万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
Development and validation of an epigenetic clock in Fischer 344 rats.
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批准号:10263717
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项目类别:
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资助金额:$4.96万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
The Hallmarks of Aging: Assessing accumulation of DNA lesions with age using single cell DNA sequencing in GESTALT
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批准号:10259327
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项目类别:
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资助金额:$1.1万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
Metabolomic Signatures Predicting Dual Cognitive and Gait Decline for the Health ABC Study
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批准号:10261195
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项目类别:
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资助金额:$10.58万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
The Hallmarks of Aging: Assessing accumulation of DNA lesions with age using single cell DNA sequencing in GESTALT
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批准号:10691058
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项目类别:
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资助金额:$1.15万
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财政年份:--
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负责人:Luigi Ferrucci
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依托单位:
海外基金